ChemicalBook > CAS DataBase List > Thiol-dPEG4-amie
Thiol-dPEG4-amie
Thiol-dPEG4-amie
- CAS No.1189760-69-7
- Chemical Name:Thiol-dPEG4-amie
- CBNumber:CB93146566
- Molecular Formula:C8H19NO3S
- Formula Weight:209.31
- MOL File:1189760-69-7.mol
Thiol-dPEG4-amie Property
- Boiling point 309.6±32.0 °C(Predicted)
- Density 1.060±0.06 g/cm3(Predicted)
- pka 9?+-.0.10(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Thiol-dPEG4-amie Chemical Properties,Usage,Production
- Uses HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- Biological Activity HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
- IC 50 PEGs
- References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Thiol-dPEG4-amie Preparation Products And Raw materials
Raw materials
Preparation Products
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1189760-69-7, Thiol-dPEG4-amieRelated Search:
- Thiol-PEG7-acid Thiol-PEG3-t-butyl ester Thiol-dPEG5-azido Thiol-PEG1-t-butyl ester Thiol-PEG3-acid Thio-PEG2-t-butyl ester Thiol-PEG2-acid Thiol-PEG6-t-butyl ester Thiol-PEG8-NH2 Thiol-PEG11-NH2 Thiol-PEG1-NH2 Thiol-PEG6-amine Thiol-PEG6-NH2 Thiol-PEG5-Amine Thiol-PEG9-NH2 Ethanethiol, 2-[2-(2-aminoethoxy)ethoxy]- Thiol-PEG12-NH2 Thiol-PEG10-NH2
- 做过的结构化合物
- 巯基-DPEG4-胺
- 2-(2-(2-(2-氨基乙氧基)乙氧基)乙氧基)乙烷-1-硫醇
- SH-PEG4-NH2
- 巯基-三聚乙二醇-氨基
- 2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙硫醇
- 巯基三聚乙二醇乙胺盐酸盐
- 1189760-69-7
- SH-PEG3-CH2CH2NH2
- Ethanethiol, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
- Amino-PEG4-Thiol
- 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethane-1-thiol
- Thiol-PEG3-NH2
- Thiol-PEG4-amine
- HS-PEG3-CH2CH2NH2·HCl
- Thiol-dPEG4-amie