Benzyl-PEG8-THP
- Product NameBenzyl-PEG8-THP
- CAS1611489-00-9
- CBNumberCB93048703
- MFC28H48O10
- MW544.67
- MDL NumberMFCD29049395
- MOL File1611489-00-9.mol
Chemical Properties
| Boiling point: | 602.0±55.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
Benzyl-PEG8-THP Chemical Properties,Usage,Production
Uses
Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].Biological Activity
Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].IC 50
PEGsReferences
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Benzyl-PEG8-THP Suppliers
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