Description
ChemicalBook > CAS DataBase List > PARATHYROID HORMONE (1-34), BOVINE

PARATHYROID HORMONE (1-34), BOVINE

Description
PARATHYROID HORMONE (1-34), BOVINE Structure
PARATHYROID HORMONE (1-34), BOVINE
  • CAS No.12583-68-5
  • Chemical Name:PARATHYROID HORMONE (1-34), BOVINE
  • CBNumber:CB9284467
  • Molecular Formula:C183H288N54O50S2
  • Formula Weight:4108.71
  • MOL File:Mol file
PARATHYROID HORMONE (1-34), BOVINE Property
  • storage temp. −20°C
  • solubility ≥410.9 mg/mL in DMSO; ≥43.8 mg/mL in H2O; ≥64.6 mg/mL in EtOH
  • form powder
  • color White to off-white
  • FDA UNII 10T9CSU89I
  • Proposition 65 List Teriparatide
  • ATC code H05AA02
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
PARATHYROID HORMONE (1-34), BOVINE Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: P3671
  • Product name : Parathyroid Hormone Fragment 1-34 bovine
  • Purity: ≥97% (HPLC), powder
  • Packaging: 0.1MG
  • Price: ₹23057.25
  • Updated: 2022/06/14
  • Buy: Buy

PARATHYROID HORMONE (1-34), BOVINE Chemical Properties,Usage,Production

  • Description Parathyroid hormone (PTH) is an 84 amino acid hormone involved in calcium regulation in counteraction to calcitonin. PTH regulates serum phosphate levels and vitamin D biosynthesis. N-terminal peptides of PTH are used to elicit and study a wide variety of responses in target cells. 
  • Uses Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis[1].
  • Clinical Use Active fragment (1-34) of endogenous human parathyroid hormone:
    Treatment of osteoporosis in postmenopausal women and men at increased risk of fractures
    Treatment of corticosteroid-induced osteoporosis
  • Side effects Teriparatide, parathyroid hormone (1–34), is the only anabolic agent available in the United States for the treatment of postmenopausal osteoporosis. Side effects that human should report to doctor or health care professional as soon as possible:
    allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
    blood in the urine; pain in the lower back or side; pain when urinating
    signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
    signs and symptoms of increased calcium like nausea; vomiting; constipation; low energy; or muscle weakness
  • in vivo

    Parathyroid Hormone (1-34)(subcutaneous?injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals.?Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls[1].

  • Metabolism No metabolism or excretion studies have been performed. Peripheral metabolism of PTH is believed to occur by non-specific enzymatic mechanisms in the liver followed by excretion via the kidneys. The 24-hour urine excretion of calcium was reduced by a clinically unimportant amount (15%).
  • References [1] B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84. DOI:10.1002/jbmr.5650070503
    [2] M Takigawa, et al. Studies on chondrocytes from mandibular condylar cartilage, nasal septal cartilage, and spheno-occipital synchondrosis in culture. I. Morphology, growth, glycosaminoglycan synthesis, and responsiveness to bovine parathyroid hormone (1-34). J Dent Res. 1984 Jan;63(1):19-22. DOI:10.1177/00220345840630010201
PARATHYROID HORMONE (1-34), BOVINE Preparation Products And Raw materials
Raw materials
Preparation Products
PARATHYROID HORMONE (1-34), BOVINE Suppliers
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PARATHYROID HORMONE (1-34), BOVINE Spectrum
12583-68-5, PARATHYROID HORMONE (1-34), BOVINERelated Search:
  • Peptides for Cell Biology
  • Parathyroid Hormone Fragments
  • Parathyroid Hormone (PTH)Peptides and Proteins
  • Other Protein/Peptide Hormones
  • Hormones
  • Peptide
  • Neuroscience
  • 抑制剂
  • 药物多肽
  • 目录肽
  • 原料药
  • 优势产品
  • 目录多肽
  • 标准品
  • 多肽
  • BioChemical
  • Other Protein/Peptide Hormones
  • Parathyroid Hormone (PTH)
  • Hormones
  • Cytokines, Growth Factors and Hormones
  • Cell Biology
  • Cell Signaling and Neuroscience
  • C183H288N54O50S2
  • L-丙氨酰-L-缬氨酰-L-丝氨酰-L-Α-谷氨酰-L-异亮氨酰-L-谷氨酰胺-L-苯丙氨酰-L-蛋氨酰-L-组氨酰-L-天冬酰胺-L-亮氨酰甘氨酰-L-赖氨酰-L-组氨酰-L-亮氨酰-L-丝氨酰-L-丝氨酰-L-蛋氨酰-L-Α-谷氨酰-L-精氨酰-L-缬氨酰-L-Α-谷氨酰-L-色氨酰-L-亮氨酰-L-精氨酰-L-赖氨酰-L-赖氨酰-L-亮氨酰-L-谷氨酰胺-L-Α-天冬氨酰-L-缬氨酰-L-组氨酰-L-天冬酰胺-L-苯丙氨酸
  • PARATHYROID HORMONE (1-34), 牛
  • 牛甲状旁腺激活素-(1-34)
  • 受体激动剂多肽PARATHYROID HORMONE(1-34) BOVINE
  • 牛甲状旁腺激素-(1-34)
  • 特立帕肽-多肽制剂一致性评价
  • 特立帕肽-多肽原料委托生产
  • PHT激活剂(TERIPARATIDE)
  • 12583-68-5
  • parathyroid hormone fragment 1-34 bovine
  • SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE: SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF
  • bovineparathyroidhormone(1-34
  • PARATHYROID HORMONE BOVINE: FRAGMENT 1-34
  • PARATHYROID HORMONE (1-34), BOVINE
  • TERIPARATIDE
  • PTH (1-34) (BOVINE)
  • BPTH 1-34
  • AVSEIQFMHNLGKHLSSMERVEWLRKKLQDVHNF
  • H-ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-OH
  • ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE BOVINE
  • ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE

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