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Levocetirizine dihydrochloride

Levocetirizine dihydrochloride Structure
Levocetirizine dihydrochloride
  • CAS No.130018-87-0
  • Chemical Name:Levocetirizine dihydrochloride
  • CBNumber:CB9135031
  • Molecular Formula:C21H27Cl3N2O3
  • Formula Weight:461.81
  • MOL File:130018-87-0.mol
Levocetirizine dihydrochloride Property
  • Melting point 215-220°C
  • alpha D25 -12.79° (c = 1 in water)
  • storage temp. room temp
  • solubility H2O: ≥23mg/mL
  • form powder
  • color White to Almost white
  • Water Solubility H2O: ≥23mg/mL
  • Merck 14,2022
  • Stability Hygroscopic
  • CAS DataBase Reference 130018-87-0(CAS DataBase Reference)
  • FDA UNII SOD6A38AGA
  • NCI Drug Dictionary levocetirizine dihydrochloride
  • UNSPSC Code 41116107
  • NACRES NA.77
Safety
  • Hazard Codes  :Xn,N
  • Risk Statements  :22-50/53
  • Safety Statements  :60-61
  • RIDADR  :UN 3077 9 / PGIII
  • WGK Germany  :3
  • RTECS  :AG0990000
  • HS Code  :29335990
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H400
  • Precautionary statements P273-P301+P312+P330
Levocetirizine dihydrochloride Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: L7795
  • Product name : Levocetirizine dihydrochloride
  • Purity: ≥98% (HPLC)
  • Packaging: 10MG
  • Price: ₹9536.83
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: L7795
  • Product name : Levocetirizine dihydrochloride
  • Purity: ≥98% (HPLC)
  • Packaging: 50MG
  • Price: ₹38017.4
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: L0264
  • Product name : Levocetirizine Dihydrochloride
  • Purity: 
  • Packaging: 1G
  • Price: ₹5100
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: L0264
  • Product name : Levocetirizine Dihydrochloride
  • Purity: 
  • Packaging: 5G
  • Price: ₹15200
  • Updated: 2022/05/26
  • Buy: Buy

Levocetirizine dihydrochloride Chemical Properties,Usage,Production

  • Uses Anti Histaminic
  • Uses Levocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.
  • General Description Levocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. ThisR-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H1-receptors.Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .
  • Biochem/physiol Actions Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.
Levocetirizine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Levocetirizine dihydrochloride Suppliers
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Levocetirizine dihydrochloride Spectrum
130018-87-0, Levocetirizine dihydrochlorideRelated Search:
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  • 盐酸左西替利嗪
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  • C21H25ClN2O32ClH
  • 3008-87-0
  • 盐酸左旋西替利嗪,10 MM DMSO 溶液
  • 盐酸左西利嗪
  • (R)-西替利嗪盐酸盐
  • 盐酸左西替利嗪对照品
  • 左西替利嗪二盐酸盐 标准品
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  • 左西替利(二盐酸盐)
  • (R)-二盐酸西替利嗪(二盐酸左西替利嗪)
  • (R)-2-(2-(4-((4-氯苯基)(苯基)甲基)哌嗪-1-基)乙氧基)乙酸二盐酸盐
  • 盐酸左西替利嗪杂质
  • 盐酸左旋西替利嗪LEVOCETIRIZINE DIHYDROCHLORIDE
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  • 左西替利嗪二盐酸盐溶液,100PPM
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  • (R)-二盐酸西替利嗪
  • 盐酸左西替利嗪LEVOCETIRIZINE HYDROCHLORIDE
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