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Dexamethasone sodium phosphate EP Impurity B

Dexamethasone sodium phosphate EP Impurity B Structure
Dexamethasone sodium phosphate EP Impurity B
  • CAS No.360-63-4
  • Chemical Name:Dexamethasone sodium phosphate EP Impurity B
  • CBNumber:CB8939872
  • Molecular Formula:C22H30FO8P
  • Formula Weight:472.44
  • MOL File:360-63-4.mol
Dexamethasone sodium phosphate EP Impurity B Property
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H410-H372-H360
  • Precautionary statements P260-P264-P270-P314-P501-P273-P391-P501

Dexamethasone sodium phosphate EP Impurity B Chemical Properties,Usage,Production

  • Originator Bentelan,Biofutura
  • Uses Glucocorticoid.
  • Definition ChEBI: Betamethasone phosphate is a steroid phosphate that is the 21-O-phospho derivative of betamethasone. It has a role as an anti-inflammatory agent and an immunosuppressive agent. It is a steroid phosphate, an 11beta-hydroxy steroid, a fluorinated steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a betamethasone. It is a conjugate acid of a betamethasone phosphate(2-).
  • Manufacturing Process A solution of bistriethylamine phosphate was prepared by slowly adding 2.36 ml of 85% phosphoric acid to 20 ml of acetonitrile containing 9.9 ml, of triethylamine at 20°C. This solution was added to a stirred mixture of 4.70 g of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-methanesulfonate and 20 ml of acetonitrile. The mixture was heated under reflux for 4 h and then evaporated under reduced pressure to a volume of 12 ml. This mixture was a concentrated solution of 9α-fluoro-11β,17α,21- trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate triethylamine salt with some inorganic phosphate.
    The salt of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene- 3,20-dione 21-phosphate may be converted to 9α-fluoro-11β,17α,21- trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate by treatment with acid (for example HCl).
  • brand name Celestone (Schering).
  • Therapeutic Function Glucocorticoid
Dexamethasone sodium phosphate EP Impurity B Preparation Products And Raw materials
Raw materials
Preparation Products
Dexamethasone sodium phosphate EP Impurity B Suppliers
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Dexamethasone sodium phosphate EP Impurity B Spectrum
360-63-4, Dexamethasone sodium phosphate EP Impurity BRelated Search:
  • 杂质-地塞米松磷酸钠杂质
  • 杂质对照品
  • 倍他米松磷酸脂杂质
  • 地塞米松磷酸钠EP杂质B 单体
  • ((3S,10AS,10BR,11S,12AS)-10B-氟-2,11-二羟基-3,10A,12A-三甲基-1,8-二氧-1,2,3,4,4A,4B,5 ,6,8,10A,10B,11,12,12A-十四氢二甲基-2-基)磷酸二氢甲酯(地塞米松杂质)
  • 地塞米松磷酸钠杂质EPZB
  • 地塞米松磷酸钠杂质EP B
  • 倍他米松4,6,11,12,12-D5 21-磷酸盐
  • 地塞米松磷酸杂质EPZB
  • 地塞米松杂质B(EP)
  • 地塞米松磷酸钠杂质B
  • 地塞米松磷酸钠杂质B(EP)
  • 倍他米松 21-磷酸酯
  • 360-63-4
  • 9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate
  • Betamethasone Sodium Phosphate Impurity 3
  • ((3S,10aS,10bR,11S,12aS)-10b-Fluoro-2,11-dihydroxy-3,10a,12a-trimethyl-1,8-dioxo-1,2,3,4,4a,4b,5,6,8,10a,10b,11,12,12a-tetradecahydrochrysen-2-yl)methyl dihydrogen Phosphate (Dexamethasone Impurity）
  • Betamethasone phosphateQ: What is Betamethasone phosphate Q: What is the CAS Number of Betamethasone phosphate
  • Betamethasone Phosphate-D4Q: What is Betamethasone Phosphate-D4 Q: What is the CAS Number of Betamethasone Phosphate-D4
  • Dexamethasone Impurity B(EP)
  • (11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4 -dien-21-yl dihydrogen phosphate
  • Betamethasone-4,6,11,12,12-d5 21-Phosphate
  • Unii-yjo1F9W10r
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-, 21-(dihydrogen phosphate)
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11beta,16beta)-
  • Einecs 206-636-7
  • Betamethasone dihydrogen phosphate
  • Betamethasone 21-phopsphate
  • 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-phosphoric acid
  • 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-phosphate
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-(dihydrogen phosphate) (7CI, 8CI)
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11β,16β)- (9CI)
  • Betamethasone 21-phosphate
  • Betamethasone 21-(dihydrogen phosphate)
  • Betamethasone phosphate
  • 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-(hydrogen phosphonate)

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