ChemicalBook > CAS DataBase List > (R)-2-Phenylpyrrolidine

(R)-2-Phenylpyrrolidine

(R)-2-Phenylpyrrolidine Structure
(R)-2-Phenylpyrrolidine
  • CAS No.56523-47-8
  • Chemical Name:(R)-2-Phenylpyrrolidine
  • CBNumber:CB8875433
  • Molecular Formula:C10H13N
  • Formula Weight:147.22
  • MOL File:56523-47-8.mol
(R)-2-Phenylpyrrolidine Property
  • Boiling point 120 °C(Press: 6 Torr)
  • Density 0.988±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
  • pka 10.13±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

(R)-2-Phenylpyrrolidine Chemical Properties,Usage,Production

  • Description (R)-2-Phenylpyrrolidine is a boronic ester that can be administered orally. It has been shown to have nootropic and memory-enhancing activities in rats, but it does not have any known effects on kinase activities, amines, factor receptors, or synthetic activity.
  • Uses (R)-2-Phenylpyrrolidine has also been shown to have prognostic value in cancer patients and can inhibit the growth of human cancer cells. This drug has been shown to bind to tropomyosin and growth factors with high affinity.
  • Definition (R)-2-Phenylpyrrolidine is a novel class of selective pan-TRK inhibitors with efficacy in a KM12 rat tumor model. Since it was reported, this moiety has become a privileged TRK structure and was incorporated effectively in closely related scaffolds and on unrelated bicycle scaffolds. Its optimal shape complementarity to the TRK protein’s hydrophobic pocket available in the “DFG-in” conformation[1].
  • Origin (R)-2-phenylpyrrolidine was first reported in 2008 by Ferrand S et al.
  • Properties and Applications (R)-2-Phenylpyrrolidine is a yellow crystal,it is used as a pharmaceutical intermediate.
  • References [1] Choi H, et al. (R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors. ACS Medicinal Chemistry Letters, 2015; 14: 562–567.
(R)-2-Phenylpyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-2-Phenylpyrrolidine Suppliers
Global(89)Suppliers
  • Supplier：
    Capot Chemical Co.,Ltd.
  • Tel：+86-（0）57185586718<br/>+86-13336195806
  • Email：sales@capot.com
  • Country：China
  • ProdList：29730
  • Advantage：60
  • Supplier：
    Career Henan Chemica Co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：laboratory@coreychem.com
  • Country：China
  • ProdList：30231
  • Advantage：58
  • Supplier：
    Golden Pharma Co., Limited
  • Tel： +undefined18958062155
  • Email：sales@zjgoldpharm.com
  • Country：China
  • ProdList：5899
  • Advantage：58
  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
  • Country：United States
  • ProdList：57505
  • Advantage：58
  • Supplier：
    Suzhou ARTK Medchem Co., Ltd.
  • Tel：+86-512-68323658<br/>+86-18168183658
  • Email：sales1@artkmedchem.com
  • Country：China
  • ProdList：39003
  • Advantage：58
(R)-2-Phenylpyrrolidine Spectrum
56523-47-8, (R)-2-PhenylpyrrolidineRelated Search:
  • Chiral heterocyclic compounds
  • pharmaceutical intermediate
  • 高端化学
  • 合成材料中间体
  • 医药中间体
  • (2R)-2-苯基吡咯烷
  • (R)-2-苯基吡咯烷
  • R-2-苯基四氢吡咯
  • (R)-2-苯基吡咯
  • 56523-47-8
  • Pyrrolidine, 2-phenyl-, (2R)-
  • 56523-47-8
  • (2R)-2-phenylpyrrolidine
  • (R)-2-Phenylpyrrolidine

Home

My