ChemicalBook > CAS DataBase List > H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH

H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH

H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Structure
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
  • CAS No.107015-83-8
  • Chemical Name:H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
  • CBNumber:CB8686415
  • Molecular Formula:C89H135N25O25
  • Formula Weight:1955.18
  • MOL File:107015-83-8.mol
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Property
  • storage temp. −20°C
  • solubility ≥195.5 mg/mL in DMSO; insoluble in EtOH; ≥59.8 mg/mL in H2O
  • form solid
  • Water Solubility Soluble to 0.70 mg/ml in water
  • Sequence H-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Chemical Properties,Usage,Production

  • Uses β-Amyloid (12-28) (Amyloid β-Protein (12-28)) is a peptide fragment of β-amyloid protein (β1-42). β1-42, a 42 amino acid protein , is the major component of senile plaque cores. β-Amyloid (12-28) shows aggregation properties. β-Amyloid (12-28) has the potential for Alzheimer’s disease research[1].
  • Biological Activity amyloid beta (aβ or abeta) is a peptide of 36–43 amino acids that is processed from the amyloid precursor protein. while best known as a component of amyloid plaques in association with alzheimer's disease, evidence has been found that aβ is a highly multifunctional peptide with significant non-pathological activity(1). aβ is the main component of deposits found in the brains of patients with alzheimer's disease. brain aβ is elevated in patients with sporadic alzheimer’s disease. aβ is the main constituent of brain parenchymal and vascular amyloid, it contributes to cerebrovascular lesions and is neurotoxic(2).figure1 formula of amyloid β-peptide (12-28) (human)figure2 signal pathway of amyloid β
  • References 1. Lahiri DK, Maloney B (September 2010). "Beyond the signaling effect role of amyloid–β42 on the processing of AβPP, and its clinical implications". Exp. Neurol. 225 (1): 51–4.2. Hardy J, Duff K, Hardy KG, Perez-Tur J, Hutton M (September 1998). "Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau". Nat. Neurosci. 1 (5): 355–8.
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Suppliers
Global(87)Suppliers
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
  • Advantage：58
  • Supplier：
    Cellmano Biotech Limited
  • Tel：0551-65326643<br/>18156095617
  • Email：info@cellmano.com
  • Country：China
  • ProdList：995
  • Advantage：58
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    Nextpeptide Inc
  • Tel：+86-0571-81612335<br/>+8613336028439
  • Email：sales@nextpeptide.com
  • Country：China
  • ProdList：19908
  • Advantage：58
H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH Spectrum
107015-83-8, H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OHRelated Search:
  • Alzheimer
  • Amyloid beta-peptide and related
  • Neuropeptides
  • Neurodegenerative Disease Peptides
  • Amyloid beta Protein Fragments
  • peptide
  • 目录肽
  • 目录多肽
  • 多肽
  • BioChemical
  • Biochemicals and Reagents
  • Amyloid beta Protein Fragments
  • Amino Acids and Peptides
  • Peptides
  • Neurodegenerative Disease Peptides
  • C89H135N25O25
  • CY5.5标记的精子表面蛋白SP17抗体
  • BF350标记的精子表面蛋白SP17抗体
  • BF488标记的精子表面蛋白SP17抗体
  • BF594标记的精子表面蛋白SP17抗体
  • APC-CY5.5标记的精子表面蛋白SP17抗体
  • BF750标记的精子表面蛋白SP17抗体
  • CY3标记的精子表面蛋白SP17抗体
  • BF680标记的精子表面蛋白SP17抗体
  • PE标记的精子表面蛋白SP17抗体
  • BF555标记的精子表面蛋白SP17抗体
  • PERCP标记的精子表面蛋白SP17抗体
  • AE标记的精子表面蛋白SP17抗体
  • IRDYE 800CW标记的精子表面蛋白SP17抗体
  • PERCP-CY7标记的精子表面蛋白SP17抗体
  • PERCP-CY5.5标记的精子表面蛋白SP17抗体
  • AP标记的精子表面蛋白SP17抗体
  • HRP标记的精子表面蛋白SP17抗体
  • PE-CY5.5标记的精子表面蛋白SP17抗体
  • CY7标记的精子表面蛋白SP17抗体
  • BF700标记的精子表面蛋白SP17抗体
  • APC标记的精子表面蛋白SP17抗体
  • CY5标记的精子表面蛋白SP17抗体
  • RBITC标记的精子表面蛋白SP17抗体
  • BF647标记的精子表面蛋白SP17抗体
  • BF405标记的精子表面蛋白SP17抗体
  • PE-CY7标记的精子表面蛋白SP17抗体
  • PACIFIC BLUE标记的精子表面蛋白SP17抗体
  • APC-CY7标记的精子表面蛋白SP17抗体
  • BIOTIN标记的精子表面蛋白SP17抗体
  • PE-CY5标记的精子表面蛋白SP17抗体
  • BETA-AMYLOID多肽(12-28)
  • 淀粉样肽 AMYLOID Β-PROTEIN (12-28)
  • 淀粉-Β-蛋白片段12-28
  • 107015-83-8
  • Beta-Amyloid (12-28) Peptide
  • beta-Amyloid Peptide (12-28)
  • beta-Amyloid Peptide (12-28)(TFA salt)
  • Amyloid Bate-Protein (12-28)/Bate-Amyloid (12-28)
  • Bate-Amyloid (12-28)
  • β-amyloid (12-28)
  • AMyloid β-Protein (12-28) AlzheiMer's Disease β-Protein (12-28)
  • Amyloid β-Protein (12-28)

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