ChemicalBook > CAS DataBase List > HOOCCH2CH2-PEG16-CH2CH2COOH
HOOCCH2CH2-PEG16-CH2CH2COOH
HOOCCH2CH2-PEG16-CH2CH2COOH
- CAS No.2226897-74-9
- Chemical Name:HOOCCH2CH2-PEG16-CH2CH2COOH
- CBNumber:CB84868345
- Molecular Formula:C38H74O21
- Formula Weight:866.98
- MOL File:2226897-74-9.mol
HOOCCH2CH2-PEG16-CH2CH2COOH Property
- form Solid
- color Off-white to light yellow
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
HOOCCH2CH2-PEG16-CH2CH2COOH Chemical Properties,Usage,Production
- Uses Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- Biological Activity Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
- IC 50 PEGs
- References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
HOOCCH2CH2-PEG16-CH2CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
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2226897-74-9, HOOCCH2CH2-PEG16-CH2CH2COOHRelated Search:
- 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58-Nonadecaoxahenhexacontanedioic acid 4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetracontanedioic acid INDEX NAME NOT YET ASSIGNED Acid-PEG3-t-butyl ester Acid-PEG5-t-butyl ester COOH-PEG10-COOtBu HO-PEG5-CH2COOtBu Acid-PEG4-t-butyl ester HOOCCH2CH2O-PEG10-CH2CH2COOH Hydroxy-PEG5-acid
- C38H74O21
- 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-七烷氧基五苯二甲酸
- 羧酸-十七聚乙二醇-羧酸
- 2226897-74-9
- COOH-PEG17-CH2CH2COOH
- HOOCCH2CH2O-PEG16-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid
- Di-Acid-PEG17
- 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid
- HOOCCH2CH2-PEG16-CH2CH2COOH