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TETRAETHYL METHYLENEDIPHOSPHONATE

TETRAETHYL METHYLENEDIPHOSPHONATE Structure
TETRAETHYL METHYLENEDIPHOSPHONATE
  • CAS No.1660-94-2
  • Chemical Name:TETRAETHYL METHYLENEDIPHOSPHONATE
  • CBNumber:CB8435905
  • Molecular Formula:C9H22O6P2
  • Formula Weight:288.21
  • MOL File:1660-94-2.mol
TETRAETHYL METHYLENEDIPHOSPHONATE Property
  • Boiling point 171-174 °C11 mm Hg(lit.)
  • Density 1.16 g/mL at 25 °C(lit.)
  • refractive index n20/D 1.442(lit.)
  • Flash point >230 °F
  • storage temp. Inert atmosphere,Room Temperature
  • solubility Chloroform (Sparingly), Methanol (Slightly)
  • form Liquid
  • Specific Gravity 1.160
  • color Clear yellow to yellow-brown
  • Water Solubility Slightly miscible with water.
  • BRN 1813241
  • InChIKey STJWVOQLJPNAQL-UHFFFAOYSA-N
  • CAS DataBase Reference 1660-94-2(CAS DataBase Reference)
  • FDA UNII WT3D5Q9EPC
  • EPA Substance Registry System Phosphonic acid, methylenebis-, tetraethyl ester (1660-94-2)
  • UNSPSC Code 12352108
  • NACRES NA.22
Safety
  • Hazard Codes  :Xi,C
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36
  • WGK Germany  :3
  • RTECS  :SZ9150000
  • Hazard Note  :Corrosive
  • TSCA  :Yes
  • HS Code  :29319090
  • Toxicity :mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03139,
  • NFPA 704:
    1
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319
  • Precautionary statements P280g-P305+P351+P338
TETRAETHYL METHYLENEDIPHOSPHONATE Price More Price(5)
  • Brand: Sigma-Aldrich(India)
  • Product number: 359181
  • Product name : Tetraethyl methylenediphosphonate
  • Purity: 97%
  • Packaging: 5ML
  • Price: ₹8313.6
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 359181
  • Product name : Tetraethyl methylenediphosphonate
  • Purity: 97%
  • Packaging: 25ML
  • Price: ₹22873.23
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-A14532-22
  • Product name : Tetraethyl methylenediphosphonate, 98+%
  • Purity: 
  • Packaging: 100g
  • Price: ₹116542
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-A14532-14
  • Product name : Tetraethyl methylenediphosphonate, 98+%
  • Purity: 
  • Packaging: 25g
  • Price: ₹17274
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-A14532-06
  • Product name : Tetraethyl methylenediphosphonate, 98+%
  • Purity: 
  • Packaging: 5g
  • Price: ₹3923
  • Updated: 2022/05/26
  • Buy: Buy

TETRAETHYL METHYLENEDIPHOSPHONATE Chemical Properties,Usage,Production

  • Chemical Properties clear yellow to yellow-brown liquid
  • Uses Reactant for synthesis of:
    • Dual substrate-site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
    • Unnatural alpha-amino acid derivatives containing gem-biphosphonates
    • Biphenyl sulfonylamino Me bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption
    • Lycopene via Wittig-Horner reaction
    • Alkylaminoethylbisphosphinic acids to target farnesyl diphosphate synthase
    • Aromatic bisphosphonates for use as inhibitors of geranylgeranyl diphosphate synthase

    Precursor for synthesis of dendritic polyglycerol anions used toward L-selectin inhibition
  • Uses Tetraethyl methylidenebisphosphonate, can be used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters as potent anti-inflammatory agents. It is also an intermediate for the synthesis of new bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity.
  • Synthesis Reference(s) Synthetic Communications, 20, p. 1865, 1990 DOI: 10.1080/00397919008053112
    Tetrahedron Letters, 34, p. 1515, 1993 DOI: 10.1016/S0040-4039(00)60333-7
  • reaction suitability reaction type: C-C Bond Formation
TETRAETHYL METHYLENEDIPHOSPHONATE Preparation Products And Raw materials
Raw materials
Preparation Products
TETRAETHYL METHYLENEDIPHOSPHONATE Suppliers
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TETRAETHYL METHYLENEDIPHOSPHONATE Spectrum
1660-94-2, TETRAETHYL METHYLENEDIPHOSPHONATERelated Search:
  • OLED
  • Other
  • Naphthyridine,Quinoline
  • 医用原料
  • 高端化学
  • 羧酸类衍生物
  • 酯
  • 生物化工
  • 化学连接
  • 医药中间体
  • 精细化学品
  • C-C Bond Formation
  • Olefination
  • Synthetic Reagents
  • Horner-Wadsworth-Emmons Reagents
  • C9H22O6P2
  • CH2POOCH2CH322
  • 四乙基 亚甲基双(磷酸酯)
  • 泰诺福韦杂质183
  • 四乙基亚甲基二膦酸酯
  • 3,4.亚甲基二磷酸四乙酯
  • 亚甲基二膦酸四乙酯
  • (四乙基亚甲基二磷酸脂) 2800/500G 1500/100G
  • 亚甲基二磷酸四乙酯(97%)
  • 亚甲基二磷酸四乙酯, 98+%
  • 四乙基亚甲基二磷酸酯
  • 双(二乙氧基氧膦基)甲烷
  • 亚甲基二磷酸四乙基酯
  • 亚甲基二磷酸四乙酯
  • 四乙基亚甲基二磷酸脂
  • 1660-94-2
  • 1-[diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethane
  • diethyl [(diethoxyphosphoryl)methyl]phosphonate
  • Tenofovir Impurity 183
  • Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetraethyl ester
  • enediphosphonate
  • 1-5kg
  • Tetraethyl methylidenediphosphonate
  • Tetraethylemethylenediphosphonate
  • Tetraethyl methylenediphosphonate 97%
  • methylenebis-phosphonicacitetraethylester
  • methylenebis(diethylphosphonate)
  • NSC 133889
  • Methylenedi(phosphonic acid diethyl) ester
  • Methylenebisphosphonic acid tetraethyl
  • Methylenebis(phosphonic acid diethyl)
  • [α,β-Methylene]diphosphoric acid tetraethyl
  • Bis(diethoxyphosphinyl)methane, Methylenediphosphonic acid tetraethylester
  • tetraethyl methylenediphosphate
  • Tetraethyl Methylenediphosphonate, 97% 5ML
  • Tetraethyl Methylenediphosphonate, 97% 25ML
  • Tetraethyl methanediylbis(phosphonate)
  • Tetraethyl methylenediphosphonatedisc 6/01
  • Tetraethyl methylenediphosphonate,97%
  • Tetraethyl(methylene)bisphosphonate, 98 %
  • methanediyl-bis-phosphonic acid tetraethyl ester
  • Tetraethyl methylenediphosphonate, 98+%
  • TETRAETHYL METHYLENEDIPHOSPHONATE

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