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Fmoc-NH-PEG6-CH2COOH

Fmoc-NH-PEG6-CH2COOH Structure
Fmoc-NH-PEG6-CH2COOH
  • CAS No.437655-96-4
  • Chemical Name:Fmoc-NH-PEG6-CH2COOH
  • CBNumber:CB83340590
  • Molecular Formula:C29H39NO10
  • Formula Weight:561.62
  • MOL File:437655-96-4.mol
Fmoc-NH-PEG6-CH2COOH Property
  • storage temp. 2-8°C
  • form Viscous Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Fmoc-NH-PEG6-CH2COOH Chemical Properties,Usage,Production

  • Description Fmoc-NH-PEG6-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
  • Uses Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 Cleavable Linker; Alkyl/ether; PEGs
  • References [1] Michael A, et al. Synthesis of Bifunctional Integrin‐Binding Peptides Containing PEG Spacers of Defined Length for Non‐Viral Gene Delivery. Volume2008, Issue17.
Fmoc-NH-PEG6-CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-NH-PEG6-CH2COOH Suppliers
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Fmoc-NH-PEG6-CH2COOH Spectrum
437655-96-4, Fmoc-NH-PEG6-CH2COOHRelated Search:
  • 抑制剂
  • PEG系列产品-Fmoc-PEG系列
  • 助剂
  • 小分子PEG
  • C29H39NO10
  • 化合物 FMOC-NH-PEG6-CH2COOH
  • FMOC-NH-PEG6-CH2COOH;≥98%
  • 芴甲氧羰基六聚乙二醇乙酸
  • 芴甲氧羰基-PEG6-乙酸
  • 1-(9H-芴-9-基)-3-氧代-2,7,10,13,16,19,22-七氧杂-4-氮杂二十四烷-24-酸
  • 芴甲氧羰氨基六聚乙二醇乙酸
  • 芴甲氧羰基六聚乙二醇羧甲基
  • FMOC酰胺-六聚乙二醇-乙酸
  • FMOC酰胺-六聚乙二醇-乙酸,FMOC-NH-PEG6-CH2COOH
  • 437655-96-4
  • FmocNH-PEG6-CH2COOH/5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-PEG6-acetic acid
  • 5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid
  • Fmoc-NH-PEG6-CH2COOH

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