ChemicalBook > CAS DataBase List > 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

CAS No.51225-30-0
Chemical Name:3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CBNumber:CB82324582
Molecular Formula:C20H18O5
Formula Weight:338.35
MOL File:51225-30-0.mol

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Property

Melting point 227 °C(Solv: methanol (67-56-1))
Boiling point 586.1±50.0 °C(Predicted)
Density 1.351±0.06 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder
pka 7.03±0.20(Predicted)
color Yellow
Stability Light Sensitive
FDA UNII 48ZS74CB9A

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H310+H330-H302-H315-H319-H412
Precautionary statements P501-P273-P260-P270-P262-P271-P264-P280-P284-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P312+P330-P302+P352+P310-P304+P340+P310-P403+P233-P405

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Chemical Properties,Usage,Production

Uses Wighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.
Definition ChEBI: A member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 6. It has been isolated from Ficus mucuso.
target HSP (e.g. HSP90) | Antifection

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Preparation Products And Raw materials

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3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one Spectrum

51225-30-0, 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-oneRelated Search:

抑制剂
医用原料
合成材料中间体
黄酮
植物提取物
标准品
5,7-二羟基-3-(4-羟基苯基)-6-(3-甲基丁-2-烯-1-基)-4H-苯并吡喃-4-酮
怀特酮
5,7,4'三羟基-6-异戊烯基异黄酮
51225-30-0
5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
Erythrinin B|||6-Isopentenylgenistein
5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-
5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-1-benzopyran-4-one
5,7,4'-Trihydroxy-6-prenylisoflavone
Wighteone
Erythrinin B
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
4',5,7-Trihydroxy-6-prenyl-isoflavone
4',5,7-Trihydroxy-6-(3-methyl-2-butenyl)isoflavone
3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one