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A[5']P5[5']A SODIUM SALT

A[5']P5[5']A SODIUM SALT Structure
A[5']P5[5']A SODIUM SALT
  • CAS No.4097-04-5
  • Chemical Name:A[5']P5[5']A SODIUM SALT
  • CBNumber:CB8189688
  • Molecular Formula:C20H24N10Na5O22P5
  • Formula Weight:1026.28
  • MOL File:4097-04-5.mol
A[5']P5[5']A SODIUM SALT Property
  • storage temp. -20°C
  • solubility H2O: 50 mg/mL
  • form powder
  • color white to white with yellow cast
  • biological source synthetic (organic)
  • Water Solubility H2O: 50mg/mL
  • BRN 4949216
  • UNSPSC Code 12352202
  • NACRES NA.51
Safety
  • WGK Germany  :3
  • F  :10-21
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
A[5']P5[5']A SODIUM SALT Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: D4022
  • Product name : P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt
  • Purity: ≥95% (HPLC), powder
  • Packaging: 2MG
  • Price: ₹4849.6
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D4022
  • Product name : P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt
  • Purity: ≥95% (HPLC), powder
  • Packaging: 10MG
  • Price: ₹15761.2
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D4022
  • Product name : P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt
  • Purity: ≥95% (HPLC), powder
  • Packaging: 25MG
  • Price: ₹26174.85
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D4022
  • Product name : P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt
  • Purity: ≥95% (HPLC), powder
  • Packaging: 50MG
  • Price: ₹44923.75
  • Updated: 2022/06/14
  • Buy: Buy

A[5']P5[5']A SODIUM SALT Chemical Properties,Usage,Production

  • Uses P1,P5-Di(adenosine-5′) pentaphosphate pentasodium salt has been used as:
    • an adenylate kinase (AK) inhibitor in: sarcoma osteogenic (Saos-2) cells
    • mitochondrial lysates during ATP synthesis
    • tetramethylrhodamine methyl ester (TMRM) based membrane potential assay
    • chromoplasts

  • General Description P1,P5-Di(adenosine-5′) pentaphosphate (Ap5A) is a diadenosine polyphosphate, which has a tail-to-tail dimer structure. Ap5A is synthesized in a twostep process involving the formation of adenosine 5′-tetraphosphate (P4A) from the ATP and trimeta-phosphate (P3). In the second step, P4A is converted to Ap5A. The synthesis of Ap5A requires a pH optimum in the range of 7.5 to 8.5 and is modulated by metal ions.
  • Biochem/physiol Actions A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.
  • IC 50 Human Endogenous Metabolite
A[5']P5[5']A SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
A[5']P5[5']A SODIUM SALT Suppliers
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  • Supplier：
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A[5']P5[5']A SODIUM SALT Spectrum
4097-04-5, A[5']P5[5']A SODIUM SALTRelated Search:
  • 酶
  • 酶与辅酶
  • 其他生化试剂
  • 生化试剂
  • BioChemical
  • Biochemicals and Reagents
  • Enzyme Inhibitors by Type
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Nucleotide Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Substrate Analogs
  • C20H24N10O22P55Na
  • P1,P5-二(腺苷')五磷酸五钠盐
  • P1,P5-二(腺苷5′)五磷酸五钠盐
  • P<sup>1</sup>,P<sup>5</sup>-二(腺苷5′)五磷酸五钠盐
  • 5'-腺苷酯五钠盐
  • 腺苷 5'-(六氢五磷酸酯) P''''-5'-腺苷酯五钠盐
  • 4097-04-5
  • Diadenosine pentaphosphate pentasodium salt
  • Diadenosine pentaphosphate pentasodium
  • DIADENOSINE PENTAPHOSPHATE SODIUM SALT
  • Adenosine 5'-(hexahydrogen pentaphosphate) P''''-5'-ester with adenosine pentasodium salt
  • P<sup>1</sup>,P<sup>5</sup>-Di(adenosine-5') pentaphosphate pentasodium salt
  • P<sup>1</sup>,P<sup>5</sup>-Di(adenosine-5
  • 5'-ester with adenosine pentasodium salt
  • P<sup>1</sup>,P<sup>5</sup>-Di(adenosine-5′) pentaphosphate pentasodium
  • A(5′)P5(5′)A
  • Adenosine-5'-pentaphosphateε-5'-adenosyl α,β,γ,δ,ε-pentasodium salt
  • P1,P5-di(adenosine-5')pentaphosphate pentasodium salt 5H2O
  • P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATESOD IUM
  • Adenosine 5'-(hexahydrogen pentaphosphate), 5'->5'-ester with adenosine, pentasodium salt
  • P1,P5-DI(ADENOSINE-5') PENTAPHOSPHATE SODIUM SALT
  • A[5']P5[5']A SODIUM SALT

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