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Fukinolide
Fukinolide
- CAS No.18455-98-6
- Chemical Name:Fukinolide
- CBNumber:CB81470538
- Molecular Formula:C22H30O6
- Formula Weight:390.47
- MOL File:18455-98-6.mol
Fukinolide Property
- Melting point 101-102 °C
- Boiling point 503.0±50.0 °C(Predicted)
- Density 1.16±0.1 g/cm3(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Fukinolide Chemical Properties,Usage,Production
- Uses Bakkenolide B is isolated from petasites japonicas leaves and has?anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma[1].
- Definition ChEBI: Bakkenolide B is a terpene lactone.
-
in vivo
Bakkenolide B (intraperitoneal injection; 1 mg/ml; 1 h before ovalbumin nebulization on days 28, 29, and 30) strongly inhibits the accumulation of eosinophils, macrophages, and lymphocytes to bronchoalveolar lavage fluid (BALF) in ovalbumin-induced asthma mice[1].
Animal Model: Ovalbumin-induced asthma mice[1] Dosage: 1 mg/ml Administration: Intraperitoneal injection; 1 h before ovalbumin nebulization on days 28, 29, and 30 Result: Exhibited anti-allergic effects in mice. - References [1] Lee KP, et al. Anti-allergic and anti-inflammatory effects of bakkenolide B isolated from Petasites japonicus leaves.J Ethnopharmacol.?2013 Jul 30;148(3):890-4. DOI:10.1016/j.jep.2013.05.037
Fukinolide Preparation Products And Raw materials
Raw materials
Preparation Products
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18455-98-6, FukinolideRelated Search:
- 倍半萜
- 螺内酯(安体舒通)杂质16
- 蜂斗菜内酯B
- 蜂斗菜螺内酯
- 18455-98-6
- Spironolactone EP Impurity 16
- 2-Butenoic acid, 2-methyl-, (2'R,3'R,3'aR,4'S,7'S,7'aR)-3'-(acetyloxy)decahydro-7',7'a-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'-yl ester, (2Z)-
- Bakkenolide B
- (Z)-2-Methyl-2-butenoic acid [(3R,3'aα)-3'α-acetoxy-4,5,1',3',3'a,4',5',6',7',7'a-decahydro-7'α,7'aα-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'β-yl] ester
- (1'R,3R,7'aβ)-1'β-Acetoxy-3'aβ,4'β-dimethyl-4-methylene-7'α-[[(2Z)-2-methyl-2-butenoyl]oxy]spiro[oxolane-3,2'-hydrindane]-2-one
- (-)-Bakkenolide B
- Fukinolide