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3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Structure
3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • CAS No.151266-23-8
  • Chemical Name:3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • CBNumber:CB8144555
  • Molecular Formula:C5H4IN5
  • Formula Weight:261.02
  • MOL File:151266-23-8.mol
3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Property
  • Boiling point 312.3±52.0 °C(Predicted)
  • Density 2.92±0.1 g/cm3(Predicted)
  • storage temp. Keep in dark place,Sealed in dry,Room Temperature
  • form powder to crystal
  • pka 10.50±0.20(Predicted)
  • color White to Light yellow to Light orange
  • Sensitive Light Sensitive
  • λmax 282nm(lit.)
  • InChI InChI=1S/C5H4IN5/c6-3-2-4(7)8-1-9-5(2)11-10-3/h1H,(H3,7,8,9,10,11)
  • InChIKey HQAIUXZORKJOJY-UHFFFAOYSA-N
  • SMILES C1=NC(N)=C2C(I)=NNC2=N1
  • UNSPSC Code 12352116
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H335-H315-H319
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: I0941
  • Product name : 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • Purity: 
  • Packaging: 1G
  • Price: ₹8800
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: I0941
  • Product name : 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • Purity: 
  • Packaging: 5G
  • Price: ₹15200
  • Updated: 2022/05/26
  • Buy: Buy

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Chemical Properties,Usage,Production

  • Uses 3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.
  • Synthesis A solution of 3H-pyrazolo[3,4-d]pyrimidin-4-amine (10 g, 0.074 mol) and n-iodo-succinamide (25 g, 0.111 mol) in DMF (80 mL) was heated to 80° C. overnight under an argon atmosphere. The resulting solid was filtered and rinsed with cold EtOH. The product was dried in vacuo overnight to yield 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (24 g, 100 per cent yield).
3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Spectrum
151266-23-8, 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Related Search:
  • pharmacetical
  • Heterocycle-Pyridine series
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  • 3-碘-1H-4-氨基吡唑[3,4-D]并嘧啶/151266-23-8
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  • 化合物 4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE
  • PERFEMIKER]4-氨基-3-碘-1H-吡唑[3,4-D]嘧啶,98%
  • 伊鲁替尼 中间体6
  • FUTIBATINIB中间体
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