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1,2,4-Triazine

1,2,4-Triazine Structure
1,2,4-Triazine
  • CAS No.290-38-0
  • Chemical Name:1,2,4-Triazine
  • CBNumber:CB81237850
  • Molecular Formula:C3H3N3
  • Formula Weight:81.08
  • MOL File:290-38-0.mol
1,2,4-Triazine Property
  • Boiling point 197℃
  • Density 1.173
  • refractive index 1.5060 (estimate)
  • Flash point 92℃
  • storage temp. 2-8°C
  • solubility Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated, Sonicated)
  • form Gel
  • pka 0.98±0.63(Predicted)
  • color Very Dark Orange to Very Dark Brown
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

1,2,4-Triazine Chemical Properties,Usage,Production

  • Description 1,2,4-Triazine is an electron-deficient heteroaromatic azadiene capable of participation in inverse electron demand Diels-Alder reactions with electron-rich dienophiles.
  • Uses 1,2,4-Triazine (>90%) is used in improvements of pesticide formulations with lactamides. 1,2,4-triazines scaffold-valuable lead molecules possess diverse pharmacological activities, easy synthetic routes for synthesis and attracted researchers for development of new chemotherapeutic agents in human and mouse model.
  • Definition ChEBI: 1,2,4-triazine is a triazine and a member of 1,2,4-triazines.
  • Synthesis 1,2,4-Triazine is prepared by a cooled (-75 °C) solution of monomeric Glyoxal (90.0 mmol) in absolute MeOH (200 mL) is added to a solution of formamidrazone hydrochloride (40 mmol) in absolute MeOH (300 mL) at -50 °C. Et3N (200 mmol) is added and the resulting reaction mixture is allowed to stand at 25 °C for 24 h. The MeOH is removed in vacuo at 20 °C and the residue extracted with Et2O (peroxide free, 5×). Vacuum distillation of the residue after evaporation of the Et2O affords 1,2,4-triazine (bp 25-28 °C/0.5 mmHg).
  • storage Best stored at 0 °C or below. It is stable to acid, less stable to base, and is hygroscopic; should be stored under anhydrous conditions since it reacts slowly with water and protic solvents.
1,2,4-Triazine Preparation Products And Raw materials
Raw materials
Preparation Products
1,2,4-Triazine Suppliers
Global(20)Suppliers
  • Supplier：
    Alchem Pharmtech,Inc.
  • Tel：8485655694
  • Email：sales@alchempharmtech.com
  • Country：United States
  • ProdList：63687
  • Advantage：58
  • Supplier：
    Career Henan Chemica Co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：laboratory@coreychem.com
  • Country：China
  • ProdList：30231
  • Advantage：58
1,2,4-Triazine Spectrum
290-38-0, 1,2,4-TriazineRelated Search:
  • 化学品
  • 1,2,5-三嗪
  • 1,2,4-三嗪
  • 290-38-0
  • 1,2,4-Triazine (>90%)
  • 1,2,5-Triazine
  • as-Triazine

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