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Neutral Red

Neutral Red Structure
Neutral Red
  • CAS No.553-24-2
  • Chemical Name:Neutral Red
  • CBNumber:CB7853810
  • Molecular Formula:C15H17ClN4
  • Formula Weight:288.78
  • MOL File:553-24-2.mol
Neutral Red Property
  • Melting point 290 °C (dec.) (lit.)
  • Boiling point 441.31°C (rough estimate)
  • Density 1.1590 (rough estimate)
  • bulk density 350-500kg/m3
  • refractive index 1.6110 (estimate)
  • storage temp. Store at +5°C to +30°C.
  • solubility H2O: soluble10mg/mL
  • form Solid
  • Colour Index 50040
  • pka 6.7, 7.4(at 25℃)
  • color Very dark green
  • PH Range 6.8(red)-8(yellow)
  • PH 3.1 (10g/l, H2O, 20℃)
  • Odor Odorless
  • Water Solubility 50 g/L
  • λmax 540nm, 533nm, 544nm, 529nm, 454nm
  • Merck 14,6488
  • BRN 3918740
  • Stability Stable. Incompatible with strong oxidizing agents.
  • Biological Applications Detecting pathogens,bacterial infections; treating age-related macular degeneration,burns,cancer,diabetes,obesity,fungal infections,viral diseases
  • Major Application Fuel cell power generation system, liquid crystal displays, solor cells, sensors, thermochromic materials, coloring wood, detergents, assessment of tobacco smoke, cosmetics, detect bacterial infections, multidrug resistance inhibitors, treatment of burns, endodontic, diabetes, obesity, cancer, age-related macular degeneration, viral diseases
  • CAS DataBase Reference 553-24-2(CAS DataBase Reference)
  • FDA UNII 261QK3SSBH
  • EPA Substance Registry System Neutral Red (553-24-2)
  • UNSPSC Code 41116130
  • NACRES NB.21
Safety
  • Hazard Codes  :Xn,Xi
  • Risk Statements  :68-36/37/38
  • Safety Statements  :36/37-37/39-36-26-24/25
  • WGK Germany  :3
  • RTECS  :SG1400000
  • TSCA  :Yes
  • HS Code  :32041300
  • Toxicity :LD50 intraperitoneal in mouse: 432mg/kg
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P280-P302+P352
Neutral Red Price More Price(30)
  • Brand: Sigma-Aldrich(India)
  • Product number: N7005
  • Product name : Neutral Red
  • Purity: Dye content ≥90?%
  • Packaging: 1G
  • Price: ₹4451.1
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N7005
  • Product name : Neutral Red
  • Purity: Dye content ≥90?%
  • Packaging: 5G
  • Price: ₹15628.8
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N7005
  • Product name : Neutral Red
  • Purity: Dye content ≥90?%
  • Packaging: 25G
  • Price: ₹51404.1
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N4638
  • Product name : Neutral Red
  • Purity: powder, BioReagent, suitable for cell culture
  • Packaging: 1G
  • Price: ₹5810
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N4638
  • Product name : Neutral Red
  • Purity: powder, BioReagent, suitable for cell culture
  • Packaging: 5G
  • Price: ₹17450
  • Updated: 2022/06/14
  • Buy: Buy

Neutral Red Chemical Properties,Usage,Production

  • Chemical Properties dark green powder
  • Uses Can be used as a vital stain, to stain living cells.
  • Uses Neutral Red is a common histology stain used to determine cell viability. It is also used as indicator for nitrogen determination; pH indicator; Dyes and metabolites.
  • Definition ChEBI: Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).
  • Application Transition of pH Indicator: pH 6.8 - 8.0, red to yellow. Basic red 5 is a dye used in histology for staining nuclei. It is also a pH indicator. As such it is used in microbial culture media for differentation of bacteria. For example MacConkey agar contains it and lactose. Acidification by lactic acid turns on the Basic red 5. Therefore, colonies formed by bacteria that ferment lactose into lactic acid will turn red and stand out from the pale colonies of non-lactose-fermenting bacteria. Basic red 5 is also used in cell viability tests based on the ability to incorporate and bind it.
  • Preparation (a) N,N-dimethyl-4-nitrosobenzenamine?and 4-Methylbenzene-1,3-diamine???reaction, form Toluylene Blue (Basic Dye, C.I. 49410), heating make cyclization; (b) oxidation N1,N1-dimethylbenzene-1,4-diamine?, and 4-Methylbenzene-1,3-diamine mixture.
  • General Description Neutral red (C.I. 50040) is a protonated diaminophenazine dye. It is aminodimethylaminomethylphenazinehydrochloride, C15H17N4Cl.
  • Biochem/physiol Actions Neutral red is a widely used cationic fluorochrome that is known to accumulate in the Golgi complex and nuclei after first staining lysosomes.
  • Biotechnological Applications Neutral Red is a non-toxic stain used for studies of living cells, for example to observe plasmolysis. The stain is used as an aqueous solution (0.1 %, w/v) and stains lipids in vacuoles and certain cell walls.
  • storage +4°C
  • Staining Procedures Neutral Red is a non-toxic stain used for studies of living cells, for example to observe plasmolysis. The stain is used as an aqueous solution (0.1 %, w/v) and stains lipids in vacuoles and certain cell walls.
  • Properties and Applications red light purple and red. Soluble in water is cherry red, soluble in ethanol for product red colour with red fluorescent light brown. The strong sulfuric acid for green, blue for diluted, and then into a product red. The dye solution to join strong sodium hydroxide solution have yellow brown precipitation.
  • Purification Methods In aqueous solution it is red at pH 6.8 and yellow at pH 8.0. [Beilstein 25 III/IV 3054.]
Neutral Red Preparation Products And Raw materials
Raw materials
Preparation Products
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Neutral Red Spectrum
553-24-2, Neutral RedRelated Search:
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  • C15H17ClN4
  • C15H16N4HCl
  • 中性红,10 MM DMSO 溶液
  • NEUTRAL RED,HISTOLOGY STAIN
  • 中性红指示液(微生物限度检查)
  • NEUTRAL RED CERTIFIED中性红 AMRESCO
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  • 中性红指示液,IND
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  • 中性红指示液(用于微生物限度检查)
  • 印度药典 中性红溶液
  • 英国药典 中性红溶液
  • 中性红指示液(药典)
  • 中性红染色
  • 中性红染色液(1X)
  • 中性红染色剂/中性红指示剂
  • 中性红, 生物染色级
  • 中性红/碱性红5/2-甲基-3-氨基-6-二甲氨基二氮杂蒽盐酸盐/3-氨基-6-二甲氨基-2-甲基吩嗪盐酸盐/ N8-3-三甲基-2,8-吩嗪二胺单盐酸盐/奎诺二甲基丁烷/3-氨基-7-二甲基氨基-2-甲基吩嗪盐酸盐/NEUTRAL RED
  • 中性红 >90%
  • 中性红指示液(用于微生物限度检查)(药典)
  • 中性红 553-24-2