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Pyridaben

Uses Acute Toxicity Carcinogenicity Neurotoxicity Environmental Fate and Toxicity

Pyridaben

CAS No.96489-71-3
Chemical Name:Pyridaben
CBNumber:CB7701029
Molecular Formula:C19H25ClN2OS
Formula Weight:364.93
MOL File:96489-71-3.mol

Pyridaben Property

Melting point 111-112°
Boiling point 429.9±55.0 °C(Predicted)
Density 1.2 g/cm3
storage temp. 0-6°C
solubility Chloroform: Slightly Soluble
form Solid
pka -2.69±0.20(Predicted)
color Off-white to light yellow
Merck 13,8057
BRN 7933972
LogP 6.370
CAS DataBase Reference 96489-71-3(CAS DataBase Reference)
FDA UNII 2E4JBA5272
NIST Chemistry Reference Pyridaben(96489-71-3)
EPA Substance Registry System Pyridaben (96489-71-3)
Pesticides Freedom of Information Act (FOIA) Pyridaben
UNSPSC Code 41116107
NACRES NA.24

Safety

Hazard Codes :T;N,N,T
Risk Statements :23/25-50/53
Safety Statements :36/37-45-60-61
RIDADR :UN 3077
WGK Germany :3
RTECS :UR6149000
HazardClass :6.1(a)
PackingGroup :II
Hazardous Substances Data :96489-71-3(Hazardous Substances Data)
Toxicity :LD50 in male, female rats, bobwhite quail, mallard ducks (mg/kg): 435, 358, >2250, >2500 orally (Hirata); LD50 in male, female rabbits (mg/kg): >2000, >2000 dermally (Hirata)

NFPA 704:

	0
4		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H301+H331-H410
Precautionary statements P261-P264-P270-P273-P301+P310-P304+P340+P311

Pyridaben Price More Price(1)

Brand: Sigma-Aldrich(India)
Product number: 46047
Product name : Pyridaben
Purity: PESTANAL?, analytical standard
Packaging: 25MG
Price: ₹4936.2
Updated: 2022/06/14
Buy: Buy

Pyridaben Chemical Properties,Usage,Production

Uses Pyridaben (NC-129, BAS 3001) is widely used as an acaricide with a long residual action and as an insecticide mainly against sucking insects. Trade names include Nexter, Oracle, Poseidon, Pyramite, Sanmite, and Starling.
Acute Toxicity Pyridaben shows moderate to low acute toxicity to mammals. The intraperitoneal LDso was 68 mg/kg in male rats (Igarashi and Sakamoto, 1994). The dermal toxicity is low but toxicity by the inhalation route is quite high. With sublethal doses in mice and rats, clinical signs included decreased food consumption, diarrhea, hypothermia, bradycardia, bradypnea, decreased spontaneous motor activity, abnormal gait, prostration, eye closing, amd piloerection. At near lethal or lethal doses (300 mg/kg or more) depression of the central nervous and cardiovascular systems were stronger, but no change occurred in motor functions, including coordination, muscle strength, and neuromuscular transmission, or in sensory functions. Early gastric lavage was effective in presenting poisoning in rats and loperamide was efficacious in reducing the diarrhea that occurred at low doses.
Carcinogenicity Pyridaben was not oncogenic in typical lifetime feeding studies in the rat and mouse. It is classified by the U.S. Environmental Protection Agency as a Group E compound (no evidence for carcinogenicity to humans).
Neurotoxicity Pyridaben caused only a low degree of acute neurotoxicity in a standard battery of neurobehavioral tests when given at a single oral dose of 200 mg/kg in males. Effects included piloerection, hypoactiviy, tremors, and lowered body temperature, but these were sporadic and transient. In a longer term (90 day) study in rats, no neurotoxicity or neuropathology was seen at oral doses up to 27 mg/kg/day, but plasma cholinesterase activity was reduced in females.
Environmental Fate and Toxicity Pyridaben has a low acute toxicity to birds, but it is extremely toxic to aquatic species. Its persistence in soil is relatively brief due to rapid microbial degradation (e.g., the half-life under aerobic conditions is reported to be less than 3 weeks). In natural water in the dark, the half-life is about 10 days, due mainly to microbial action since pyridaben is stable to hydrolysis over the pH range 5-9. The half-life including aqueous photolysis is about 30 min at pH 7 (Tomlin, 2000).
Chemical Properties White to tan crystalline solid or powder. Faint vanilla odor. Commercial product is available as an emulsifiable concentrate or wettable powder.
Chemical Properties Beige Solid
Uses Pyridaben is a pyridazinone derivative used as an acaricide.
Definition ChEBI: Pyridaben is a pyridazinone, an organochlorine insecticide and an organochlorine acaricide. It has a role as a mitochondrial NADH:ubiquinone reductase inhibitor.
Agricultural Uses Insecticide, Acaricide: Used to control mites, whiteflies, leafhoppers and psyllids on fruit trees, vegetables, ornamentals and other field crops. Pyramite is a selective contact miticide/insecticide that controls pests in apple, grapes, pear, pistachio, stone fruits, and the tree nuts group[83].
Trade name BAS®-300; NCI®-129; NESTER®; PYRAMITE®; SANMITE®
Potential Exposure Pyridaben is a pyridazinone insecti- cide/acaricide/miticide used to control mites, whiteflies, leafhoppers and psyllids on fruit trees, vegetables, orna- mentals and other field crops. It is also used to control pests in apple, grapes, pear, pistachio, stone fruits, and the tree nuts group .
Shipping UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2902 Pesticides, liquid, toxic. UN2902 Pesticides, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Incompatibilities Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, perox- ides, permanganates, perchlorates, chlorine, bromine, fluo- rine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste Disposal It is the responsibility of chemical waste generators to determine the toxicity and physical properties and of a discarded chemical and to properly identify its classification and certification as a haz- ardous waste and to determine the disposal method. United States Environmental Protection Agency guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult and follow all regional, national, state and local hazardous waste laws to ensure complete and accurate classification and disposal methods. Follow recommendations for the disposal of pesticides and pesticide containers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.