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FMOC-ARG(ME,PBF)-OH

FMOC-ARG(ME,PBF)-OH Structure
FMOC-ARG(ME,PBF)-OH
  • CAS No.1135616-49-7
  • Chemical Name:FMOC-ARG(ME,PBF)-OH
  • CBNumber:CB7353981
  • Molecular Formula:C35H42N4O7S
  • Formula Weight:662.8
  • MOL File:Mol file
FMOC-ARG(ME,PBF)-OH Property
  • Density 1.33
  • storage temp. Store at -15°C to -25°C.
  • form powder
  • pka 3.80±0.21(Predicted)
  • UNSPSC Code 12352209
  • NACRES NA.22
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

FMOC-ARG(ME,PBF)-OH Chemical Properties,Usage,Production

  • Description FMOC-Arg (ME, PBF)-OH is a kind of protected form of arginine. Arginine is double-protected by butyloxycarbonyl (BOC) and 2, 2, 4, 6, 7-pentamethyldihydrobenzofuran-5-sulfonyl (PBF). It is a derivative for introducing mono-methyl-arginine during Fmoc SPPS. Coupling can be carried out using any standard activation method. PBF protecting group can be removed by TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.
  • Chemical Properties White powder
  • Uses Fmoc-?Arg(Me,?pbf)?-?OH can be used as reactant/reagent in design, synthesis and structure-activity relationship of macrocyclic peptidomimetics that bind to WDR5 and block WDR5-MLL protein-protein interaction.
  • reaction suitability reaction type: Fmoc solid-phase peptide synthesis
  • References https://www.merckmillipore.com/CN/zh/product/Fmoc-Arg%28Me%2CPbf%29-OH,MDA_CHEM-852105?ReferrerURL=https%3A%2F%2Fguge6.firstguo.com%2F&bd=1
    https://en.wikipedia.org/wiki/Peptide_synthesis
    Kim, Tae-il, et al. "Arginine-conjugated polypropylenimine dendrimer as a non-toxic and efficient gene delivery carrier." Biomaterials 28.11 (2007): 2061-2067.
FMOC-ARG(ME,PBF)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
FMOC-ARG(ME,PBF)-OH Suppliers
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FMOC-ARG(ME,PBF)-OH Spectrum
1135616-49-7, FMOC-ARG(ME,PBF)-OHRelated Search:
  • amino acids
  • Fmoc Amino Acids - Arg
  • 生化试剂
  • 杂环
  • 保护氨基酸
  • Fmoc-保护氨基酸
  • 氨基酸
  • 非天然氨基酸
  • 5616-49-7
  • N-ALPHA-FMOC-N-OMEGA-甲基-N-OMEGA'-(2,2,4,6,7-五甲基-2,3-二氢苯并呋喃-5-磺酰基)-L-精氨酸
  • (S,Z)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-5-(2-甲基-3-((2,2,4,6,7-五甲基-2,3-二氢苯并呋喃-5-基)磺酰)胍基)戊酸
  • N5-[[[(2,3-二氢-2,2,4,6,7-五甲基-5-苯并呋喃基)磺酰基]氨基](甲基亚氨基)甲基]-N2-[(9H-芴-9-基甲氧基)羰基]-L-鸟氨酸
  • 1135616-49-7
  • N-alpha-Fmoc-N-omega-methyl-N-omega’-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl)-L-arginine
  • (E)-N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-Nw'-methyl-Nw-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)-L-arginine
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[[N'-methyl-N-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonyl]carbamimidoyl]amino]pentanoic acid
  • Nα-Fmoc-Nω-methyl-Nω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
  • L-Ornithine, N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino](methylimino)methyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • FMOC-ARG(ME,PBF)-OH 1 G
  • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-[(E)-N''-methyl-N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido]pentanoic acid
  • Fmoc-Arg(Me,Pbf)-OH, >97%
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Arg(Me,Pbf)-OH
  • N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino](methylimino)methyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
  • (S,Z)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-5-(3-Methyl-2-((2,2,4,6,7-pentaMethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanoic acid
  • FMoc-Arg(Pbf,Me)-OH
  • Nα-Fmoc-Nω-methyl-Nω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine≥ 98% (HPLC)
  • Fmoc-Arg(Me,Pbf)
  • N-α-(9-Fluorenylmethoxycarbonyl)-N-ω-methyl-N-ω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
  • FMOC-ARG(ME,PBF)-OH
  • N-ALPHA-FMOC-N-OMEGA-METHYL-N-OMEGA'-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE

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