ChemicalBook > CAS DataBase List > PEG21-Tos
PEG21-Tos
PEG21-Tos
- CAS No.2179113-08-5
- Chemical Name:PEG21-Tos
- CBNumber:CB73163097
- Molecular Formula:C47H88O23S
- Formula Weight:1053.25
- MOL File:2179113-08-5.mol
PEG21-Tos Property
- Boiling point 913.1±65.0 °C(Predicted)
- Density 1.149±0.06 g/cm3(Predicted)
- solubility Soluble in DMSO, DCM, DMF
- pka 14.36±0.10(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
PEG21-Tos Chemical Properties,Usage,Production
- Description PEG21-Tos is a PEG linker containing a hydroxyl group with a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
- Uses PEG20-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- IC 50 PEGs
- References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
PEG21-Tos Preparation Products And Raw materials
Raw materials
Preparation Products
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2179113-08-5, PEG21-TosRelated Search:
- C47H88O23S
- TOS-PEG20-ALCOHOL
- 二十一聚乙二醇-甲苯磺酸基
- 2179113-08-5
- OH-PEG20-Tos
- PEG21-Tosylate
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- PEG20-Tos
- PEG21-Tos