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Ilexhainanoside D

Ilexhainanoside D Structure
Ilexhainanoside D
  • CAS No.1137648-52-2
  • Chemical Name:Ilexhainanoside D
  • CBNumber:CB73158549
  • Molecular Formula:C36H56O11
  • Formula Weight:664.83
  • MOL File:1137648-52-2.mol
Ilexhainanoside D Property
  • Boiling point 788.1±60.0 °C(Predicted)
  • Density 1.35±0.1 g/cm3(Predicted)
  • pka 4.47±0.70(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Ilexhainanoside D Chemical Properties,Usage,Production

  • Uses Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect[1].
  • in vivo

    The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240?mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines[1].

  • References [1] Zhao W, et al. The combination of Ilexhainanoside D and ilexsaponin A1 reduces liver inflammation and improves intestinal barrier function in mice with high-fat diet-induced non-alcoholic fatty liver disease. Phytomedicine. 2019 Jul 26;63:153039. DOI:10.1016/j.phymed.2019.153039
Ilexhainanoside D Preparation Products And Raw materials
Raw materials
Preparation Products
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Ilexhainanoside D Spectrum
1137648-52-2, Ilexhainanoside DRelated Search:
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  • Ilexhainanoside D

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