ChemicalBook > CAS DataBase List > 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione

3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione

3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione Structure
3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione
  • CAS No.830346-50-4
  • Chemical Name:3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione
  • CBNumber:CB73051950
  • Molecular Formula:C28H24F5N3O3
  • Formula Weight:545.5
  • MOL File:830346-50-4.mol
3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione Property
  • Boiling point 625.7±65.0 °C(Predicted)
  • Density 1.357±0.06 g/cm3(Predicted)
  • storage temp. -20°C Freezer
  • solubility Dichloromethane; Ethyl Acetate; Methanol
  • pka 8.49±0.10(Predicted)
  • FDA UNII 296CMR9U5E
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione Chemical Properties,Usage,Production

  • Uses Desbutyrate Elagolix is an intermediate for the synthesis of Elagolix-d6 Sodium Salt (E501016), which is the labelled analogue of Elagolix Sodium Salt (E501018), a novel uracil phenylethylamine that acts as potent human gonadotropin-?releasing hormone receptor (hGnRH-?R) antagonist.
3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione Preparation Products And Raw materials
Raw materials
Preparation Products
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3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione Spectrum
830346-50-4, 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedioneRelated Search:
  • 化学试剂
  • 化工中间体
  • 医用原料
  • 中药对照品
  • 杂质对照品
  • 系列1
  • C28H24F5N3O3H3PO4
  • C28H24F5N3O3
  • 噁拉戈利中间体7/830346-50-4
  • 噁拉戈利钠中间体IV
  • (R)-3-(2-氨基-2-苯乙基)-5-(2-氟-3-甲氧基苯基)-1-(2-氟-6-(三氟甲基)苄基)-6-甲基嘧啶-2,4(1H,3H)-二酮
  • 噁拉戈利中间体29
  • 去丁酸依拉戈利克斯
  • 去丁酸埃拉戈利克
  • (R)-3-(2-氨基-2-苯基乙基)-5-(2-氟-3-甲氧基苯基)-1-[2-氟-6-(三氟甲基)苄基]-6-甲基嘧啶-2,4(1H,3H)-二酮
  • 3-((2R)-2-氨基-2-苯基-乙基)-5-(2-氟-3-甲氧基-苯基)-1-(2-氟-6-三氟甲基-苄基)-6-甲基-1H-嘧啶-2,4-二酮
  • 噁拉戈利标准品002
  • 噁拉戈利钠N-3
  • 噁拉戈利标准品2-R
  • 反丁酸噁拉戈利钠杂质
  • 3 - [(2R)- 2-氨基-2-苯乙基 ] - 5 -(2-氟-3-甲氧苯基)- 1 - [ [ 2-氟-6 -(三氟甲基)苯基]甲基] - 6-甲基-2,4(1H,3H)-嘧啶二酮
  • 3-[(2R)-2-氨基-2-苯基乙基]-5-(2-氟-3-甲氧基苯基)-1-[[2-氟-6-(三氟甲基)苯基]甲基]-6-甲基-2,4(1H,3H)-嘧啶二酮
  • 噁拉戈利中间体7
  • 830346-50-4
  • Intermediate 7 of Alagoli
  • Elagolix Intermediate 29
  • 1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-((R)-2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-6-methyl pyrimidine-2,4(1H,3H)-dione
  • 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione(For export only)
  • 3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione
  • Elagolix-002-R
  • EOS-61867
  • 3-[(2R)-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[2-fluoro-6-(trifluoromethyl)benzyl]-6-methyl-2,4(1H,3H)-pyrimidinedione trifluoroacetate
  • Elagolix-002
  • 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione phosphate salt
  • Desbutyrate Elagolix
  • Elagolix sodium intermediate IV
  • 2,4(1H,3H)-Pyrimidinedione,3-[(2R)-2-amino-2-phenylethyl]-5-...
  • 3-[2(R)-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[2-fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione
  • (R)-3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione
  • 2,4(1H,3H)-Pyrimidinedione, 3-[(2R)-2-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-
  • elagolix intermediate 7
  • 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione