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NNC 61-0029
NNC 61-0029
- CAS No.222834-30-2
- Chemical Name:NNC 61-0029
- CBNumber:CB72668007
- Molecular Formula:C25H25NO5
- Formula Weight:419.48
- MOL File:222834-30-2.mol
NNC 61-0029 Property
- Melting point 89-90 °C
- Boiling point 608.6±55.0 °C(Predicted)
- Density 1.241±0.06 g/cm3(Predicted)
- pka 3.61±0.10(Predicted)
- FDA UNII Q5ELR5A7Y5
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
NNC 61-0029 Chemical Properties,Usage,Production
- Uses Ragaglitazar is a PPARα and PPARγ agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models. Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic.
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References
[1] Chakrabarti R, Vikramadithyan RK, Misra P, et al. Ragaglitazar: a novel PPAR alpha PPAR gamma agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models. Br J Pharmacol. 2003;140(3):527-537. DOI:10.1038/sj.bjp.0705463
[2] Saad MF, Greco S, Osei K, et al. Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic subjects: a 12-week, double-blind, placebo-controlled dose-ranging study with an open pioglitazone arm. Diabetes Care. 2004;27(6):1324-1329. DOI:10.2337/diacare.27.6.1324
NNC 61-0029 Preparation Products And Raw materials
Raw materials
Preparation Products
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- 抑制剂
- 拉格列扎
- 化合物 T28501
- 222834-30-2
- WMUIIGVAWPWQAW-DEOSSOPVSA-N
- Benzenepropanoic acid, α-ethoxy-4-[2-(10H-phenoxazin-10-yl)ethoxy]-, (αS)-
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- NNC 61-0029