ChemicalBook > CAS DataBase List > Valsartan D9
Valsartan D9
Valsartan D9
- CAS No.1089736-73-1
- Chemical Name:Valsartan D9
- CBNumber:CB72640030
- Molecular Formula:C24H29N5O3
- Formula Weight:435.53
- MOL File:1089736-73-1.mol
Valsartan D9 Property
- storage temp. Store at -20°C
- solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form A solid
- color White to yellow
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H361-H402-H412
- Precautionary statements P201-P202-P273-P280-P308+P313-P405-P501
Valsartan D9 Chemical Properties,Usage,Production
- Chemical Properties White Solid
- Uses An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
- Biological Activity Valsartan-d9 is intended for use as an internal standard for the quantification of valsartan by GC- or LC-MS. Valsartan is a nonpeptide antagonist of the angiotensin II type 1 (AT1) receptor (IC50 = 2.7 nM). It is 20,000-fold selective for AT1 over AT2 and, unlike some other AT receptor antagonists, does not alter peroxisome proliferator-activated receptor γ (PPARγ) activity in vitro. In vivo, valsartan (30 mg/kg) increases cardiac output and reduces left ventricular fibrosis in a model of heart failure with reduced ejection fraction in mice with streptozotocin-induced diabetes. Formulations containing valsartan have been used in the treatment of hypertension and heart failure.
- IC 50 AT1 Receptor
Valsartan D9 Preparation Products And Raw materials
Raw materials
Preparation Products
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1089736-73-1, Valsartan D9Related Search:
- Valsartan Acid Isopropyl Ester Valsartan valsartan Valsartan-d8 VALSARTAN-D3 KAZCQVXZLKDFCA-NDEPHWFRSA-N Telmisartan Impurity 10 BOC-D-4,4'-BIPHENYLALANINE 1426129-50-1 enantioMer (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate methyl N-valeryl-N-[(2'-cyanobiphenyl-4-yl)methyl]-L-valinate Valsartan Impurity 10 N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine methyl ester Valsartan Impurity 12 ethyl N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-N-pentanoyl-L-valinate Valsartan Desvaleryl Impurity Valsartan n-Propyl 4-Bromomethyl-2-cyanobiphenyl
- 抑制剂
- 杂质对照品
- 对照品-杂质对照品
- 对照品
- 2H9]-缬沙坦(MAJOR)
- 缬沙坦-D9(主要成分)
- 缬沙坦-D9(主要)
- 缬沙坦-D9(D7-D9 混合物)
- [2H9]-缬沙坦
- [2H9]-缬沙坦(混合物)
- RAC-缬沙坦-D9
- 1089736-73-1
- (2S)-3-methyl-2-(N-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}(2,2,3,3,4,4,5,5,5-2H?)pentanamido)butanoic acid
- Cefuroxime Impurity 73
- 2H9]-Valsartan(major)
- Valsartan D9Q: What is Valsartan D9 Q: What is the CAS Number of Valsartan D9 Q: What is the storage condition of Valsartan D9 Q: What are the applications of Valsartan D9
- VALSARTAN-D9 (D7-D9 MIXTURE)
- [2H9]-Valsartan
- [2H9]-Valsartan (mixture)
- rac-Valsartan D9
- (2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
- ACWBQPMHZXGDFX-KDDXQTGLSA-N
- L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-