Description Mechanism Medical application Storage
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Levomefolic Acid

Description Mechanism Medical application Storage
Levomefolic Acid Structure
Levomefolic Acid
  • CAS No.31690-09-2
  • Chemical Name:Levomefolic Acid
  • CBNumber:CB72379121
  • Molecular Formula:C20H25N7O6
  • Formula Weight:459.46
  • MOL File:31690-09-2.mol
Levomefolic Acid Property
  • Melting point 215-218oC
  • Density 1.62
  • storage temp. Sealed in dry,Room Temperature
  • solubility Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly)
  • pka 3.51±0.10(Predicted)
  • form Solid
  • color Off-White to Light Green
  • InChIKey ZNOVTXRBGFNYRX-STQMWFEESA-N
  • SMILES C(O)(=O)[C@H](CCC(O)=O)NC(=O)C1=CC=C(NC[C@H]2CNC3=C(N2C)C(=O)NC(N)=N3)C=C1
  • FDA UNII 8S95DH25XC
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338
Levomefolic Acid Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: L0335
  • Product name : Levomefolic Acid
  • Purity: 
  • Packaging: 50MG
  • Price: ₹3200
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: L0335
  • Product name : Levomefolic Acid
  • Purity: 
  • Packaging: 250MG
  • Price: ₹10900
  • Updated: 2022/05/26
  • Buy: Buy

Levomefolic Acid Chemical Properties,Usage,Production

  • Description Levomefolic Acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. It is a coenzymated form of folic acid. It has been proposed for treatment of cardiovascular disease.
  • Mechanism It is synthesized in the absorptive cells of the small intestine from polyglutamylated dietary folate. It is a methylated derivative of tetrahydrofolate. Levomefolic acid is generated by methylenetetrahydrofolate reductase (MTHFR) from 5,10-methylenetetrahydrofolate (MTHF) and used to recycle homocysteine back to methionine by methionine synthase (MS).
  • Medical application Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. IC50 value: Target: Folate analogLevomefolic acid has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. Levomefolic acid (5-MTHF) has the prominent antioxidant activity. A high dose of 5-MTHF or folic acid does not influence Natural killer (NK) cell function in vitro.
    Preliminary research suggests that levomefolic acid (L-methylfolate) taken with a first-line antidepressant may provide an adjunctive antidepressant effect for individuals who do not respond or have only a partial therapeutic response to SSRI or SNRI medication,and might be a more cost-effective adjunctive agent than second-generation antipsychotics.
  • Storage Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
  • Uses A natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. It is a coenzymated form of folic acid. It has been proposed for treatment of cardiovascular disease.
  • Uses As a natural, active form of folic acid, Levomefolic Acid can be used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supple
  • Definition ChEBI: 5-methyltetrahydrofolic acid is a tetrahydrofolic acid that is 5,6,7,8-tetrahydrofolic acid substituted by a methyl group at position 5. It has a role as a human metabolite. It is functionally related to a 5,6,7,8-tetrahydrofolic acid. It is a conjugate acid of a 5-methyltetrahydrofolate(2-).
Levomefolic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Levomefolic Acid Suppliers
Global(206)Suppliers
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21628
  • Advantage：55
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
  • Advantage：58
Levomefolic Acid Spectrum
31690-09-2, Levomefolic AcidRelated Search:
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  • 二甲基亚砜:水=1:1中5-甲基四氢叶酸
  • 二甲基亚砜:水=1:1中5-甲基四氢叶酸-[13C,D3]
  • L-5-甲基四氢叶酸标准品
  • (S)-2-(4-((((S)-2-氨基-5-甲基-4-氧代-3,4,5,6,7,8-六氢蝶呤-6-基)甲基)氨基)苯甲酰胺基)戊二酸
  • 甲醇中L-5-甲基四氢叶酸标准溶液
  • L-5-甲基四氢叶酸-13C,D3
  • 左美福酸 L-5-甲基四氢叶酸
  • 左旋甲叶酸
  • 左美福酸
  • 左旋叶酸
  • 左旋叶酸(5-甲基-四氢叶酸)
  • 5-甲基四氢叶酸
  • L-5-甲基四氢叶酸
  • L-5-甲基四氢叶酸(6S)
  • 31690-09-2
  • 8S95DH25XC
  • 5-Methyltetrahydrofolic Acid-[13C,d3] in DMSO:H2O=1:1
  • (6S)-5-Methyltetrahydrofolic Acid in DMSO:H2O=1:1
  • L-Methyl Tetra Folate
  • (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioicaci
  • L-5-Methyltetrahydrofolic acid
  • 5-MTHF
  • L-5-Methyltetrahydrofolate
  • N-[4-[[[(6S)-2-Amino-5-methyl-1,4,5,6,7,8-hexahydro-4-oxopteridine-6-yl]methyl]amino]benzoyl]-L-glutamic acid
  • (6S)-5-Methyltetrahydrofolic acid
  • L-5-Methyltetrahydrofola acide
  • (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
  • Levomefolate (5-methyl-tetrahydrofolic acid)
  • L-methyl acid
  • L-Glutamic acid, N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-
  • N-[4-[[((6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid
  • (S)-2-[4-[[[(S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl]amino]benzamido]pentanedioic Acid
  • Levomefolic Acid USP/EP/BP
  • (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pen
  • Levomefolic Acid D3Q: What is Levomefolic Acid D3 Q: What is the CAS Number of Levomefolic Acid D3 Q: What is the storage condition of Levomefolic Acid D3 Q: What are the applications of Levomefolic Acid D3
  • 8-pentamethoxyflavone
  • (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzami

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