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Disodium edetate dihydrate

CAS No.6381-92-6
Chemical Name:Disodium edetate dihydrate
CBNumber:CB7153352
Molecular Formula:C10H19N2NaO9
Formula Weight:334.26
MOL File:6381-92-6.mol

Disodium edetate dihydrate Property

Melting point 250 °C (dec.)(lit.)
Boiling point >100 °C
bulk density 700kg/m3
Density 1.01 g/mL at 25 °C
refractive index n20/D 1.363
FEMA 4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
Flash point >100℃
storage temp. room temp
solubility 3 M NaOH: 100 mg/mL
form crystalline
pka pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C)
color ≤5 (0.5 M)(APHA)
Odor Odorless
PH Range 4 - 5 at 10 g/l at 23 °C
PH 4.0-5.5 (25℃, 0.1M in H2O)
biological source synthetic (organic)
Water Solubility soluble
λmax λ: 260 nm Amax: 0.145
λ: 280 nm Amax: 0.025
BRN 3900609
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey QCDUWWPHAVXXQS-UHFFFAOYSA-L
CAS DataBase Reference 6381-92-6(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
EWG's Food Scores 1
FDA UNII 7FLD91C86K
EPA Substance Registry System Ethylenediaminetetraacetic acid disodium salt dihydrate (6381-92-6)
UNSPSC Code 41116107
NACRES NA.77

Safety

Hazard Codes :Xi,Xn
Risk Statements :36-52/53-36/38-36/37/38-22
Safety Statements :26-61-37/39-36/37/39-36
WGK Germany :2
RTECS :AH4025000
F :3
TSCA :Yes
HS Code :29224995
Toxicity :LD50 orally in Rabbit: > 2000 mg/kg

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H332-H373
Precautionary statements P260-P271-P304+P340+P312-P314-P501

Disodium edetate dihydrate Price More Price(75)

Brand: Sigma-Aldrich(India)
Product number: ED2SS
Product name : Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity: reagent grade, 98.5-101.5% (titration)
Packaging: 50G
Price: ₹3637.2
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: ED2SS
Product name : Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity: reagent grade, 98.5-101.5% (titration)
Packaging: 100G
Price: ₹6841.4
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: ED2SS
Product name : Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity: reagent grade, 98.5-101.5% (titration)
Packaging: 250G
Price: ₹11723.48
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: ED2SS
Product name : Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity: reagent grade, 98.5-101.5% (titration)
Packaging: 500G
Price: ₹16735.45
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: ED2SS
Product name : Ethylenediaminetetraacetic acid disodium salt dihydrate
Purity: reagent grade, 98.5-101.5% (titration)
Packaging: 1KG
Price: ₹22732.5
Updated: 2022/06/14
Buy: Buy

Disodium edetate dihydrate Chemical Properties,Usage,Production

Chemical Properties White or almost white, crystalline powder.
Uses Chelating agent; sequestering agent
Uses Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.
Uses Ethylenediamine tetraacetic acid disodium dihydrate is used as chelating agent for metals and as pharmaceutic aid (chelating agent); as preservative in cosmetic products; anticoagulant.
Definition ChEBI: A hydrate that is the dihydrate form of EDTA disodium salt.
General Description Ethylenediaminetetraacetic acid disodium salt dehydrate is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases.
reaction suitability reagent type: chelator
Biochem/physiol Actions Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.
Purification Methods Analytical reagent grade material can be used as primary standard after drying at 80o. Commercial grade material can be purified by crystallisation from water or by preparing a 10% aqueous solution at room temperature, then adding ethanol slowly until a slight permanent precipitate is formed, filtering, and adding an equal volume of ethanol. The precipitate is filtered off onto a sintered-glass funnel, is washed with acetone, followed by diethyl ether, and dried in air overnight to give the dihydrate. Drying at 80o for at least 24hours converts it to the anhydrous form. [Beilstein 4 IV 2451.]