ChemicalBook > CAS DataBase List > Chlorflavonin
Chlorflavonin
- CAS No.23363-64-6
- Chemical Name:Chlorflavonin
- CBNumber:CB71120160
- Molecular Formula:C18H15ClO7
- Formula Weight:378.76
- MOL File:23363-64-6.mol
Chlorflavonin Property
- Boiling point 612.7±55.0 °C(Predicted)
- Density 1.52±0.1 g/cm3(Predicted)
- storage temp. 2-8°C
- solubility DMSO: 2mg/mL, clear
- pka 6.61±0.40(Predicted)
- form powder
- color white to beige
- UNSPSC Code 51111800
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Chlorflavonin Chemical Properties,Usage,Production
- Definition ChEBI: A dihydroxyflavone that is flavone substituted by a chloro group at position 3', hydroxy groups at positions 5 and 2' and methoxy groups at positions 3, 7 band 8 respectively.
- Biological Activity Originally isolated from Aspergillus candidus Link, Chlorflavonin is a non-cytotoxic (up to 100 μM; MRC-5 and THP-1) antibiotic with antifungal activity against certain species of mold fungi (MIC = 0.08 μg/mL against A. amstelodami, A. fumigalus, A. ochraceous; Paecilomyces variotii MIC = 2.5 μg/mL, Botrytis cinerea MIC = 5 μg/mL). Chlorflavonin also exhibits antibiotic activity against M. tuberculosis (MIC90 = 1.56 μM) by targeting acetohydroxyacid synthase (AHAS) catalytic subunit ilvB1. Chlorflavonin is superior to streptomycin against M. tuberculosis inside infected macrophages, synergizes with isoniazid and delamanid, leading to a complete sterilization in liquid cultures.
Chlorflavonin Preparation Products And Raw materials
Raw materials
Preparation Products
Global(6)Suppliers
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Supplier：
BOC Sciences
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- Supplier： Zhejiang Huida Biotech Co., LTD
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- Supplier： Energy Chemical
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- Supplier： Zhejiang Huida Biotech Co., LTD
- Tel：0571-0571-89903882<br/>15990081639
- Email：sunshixuan@huidabiotech.com
- Country：China
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- Supplier： Merck KGaA
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- C18H15ClO7
- 氯黄菌素
- 23363-64-6
- Chlorflavonin >=98% (HPLC)
- 4H-1-Benzopyran-4-one, 2-(3-chloro-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-
- 3'-Chloro-2',5-dihydroxy-3,7,8-trimethoxyflavone
- 2-(3-Chloro-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-1-benzopyran-4-one
- Chlorflavonin
