ChemicalBook > CAS DataBase List > 2-Bromo-3',4'-(methylenedioxy)propiophenone

2-Bromo-3',4'-(methylenedioxy)propiophenone

2-Bromo-3',4'-(methylenedioxy)propiophenone Structure
2-Bromo-3',4'-(methylenedioxy)propiophenone
  • CAS No.52190-28-0
  • Chemical Name:2-Bromo-3',4'-(methylenedioxy)propiophenone
  • CBNumber:CB6966513
  • Molecular Formula:C10H9BrO3
  • Formula Weight:257.08
  • MOL File:52190-28-0.mol
2-Bromo-3',4'-(methylenedioxy)propiophenone Property
  • Boiling point 345.7±42.0 °C(Predicted)
  • Density 1.584±0.06 g/cm3(Predicted)
  • solubility Chloroform: Soluble; DMSO: 1 mg/mL*; Ethanol: 1 mg/mL
  • form A crystalline solid
  • InChI InChI=1S/C10H9BrO3/c1-6(11)10(12)7-2-3-8-9(4-7)14-5-13-8/h2-4,6H,5H2,1H3
  • InChIKey NTPQGLLTGPTOAA-UHFFFAOYSA-N
  • SMILES C(C1=CC=C2OCOC2=C1)(=O)C(Br)C
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H314
  • Precautionary statements P264-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310-P363-P405-P501

2-Bromo-3',4'-(methylenedioxy)propiophenone Chemical Properties,Usage,Production

  • Chemical Properties Pale Yellow Solid
  • Uses 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one (2-Bromo-3',4'-(methylenedioxy)propiophenone) can be used in the preparation of antifungal agents and MDMA analogs.
  • Application 2-Bromo-3',4'-(methylenedioxy)propiophenone, also known as 4′-(methylenedioxy)propiophenone, is an analytical reference standard categorized as a precursor in the synthesis of cathinones. This product is intended for research and forensic applications.
  • Synthesis Bromine (10.0 mmol) was added to a solution of the ketone (10.0 mmol) in Et2O (25 mL). The solution was stirred for 30 min (until the color of the solution changed from red to light-yellow). Then, the reaction was quenched with water (10 mL), and the mixture was diluted with Et2O (25 mL). The organic layer was washed with a saturated solution of aqueous NaHCO3 (30 mL), a saturated solution of aqueous Na2S2O3 (30 mL), and brine (30 mL), and then it was dried over MgSO4, filtered, and concentrated. The α-bromoketone was purified by flash chromatography on silica gel. 2-Bromo-3',4'-(methylenedioxy)propiophenone [52190-28-0]. This compound was prepared according to the General Procedure from 3,4-methylenedioxypropiophenone (1.78 g, 10.0 mmol). The product was obtained as a white solid (eluted with 50% CH2Cl2 in hexanes; 2.13 g, 82% yield). 1H NMR (CDCl3, 500 MHz) δ 7.64 (d, J= 8.0 Hz, 1H), 7.49 (s, 1H), 6.87 (d, J= 8.0 Hz, 1H), 6.07 (s, 2H), 5.21 (q, J= 7.0 Hz, 1H), 1.88 (d, J= 7.0 Hz, 3H).1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one synthesis
2-Bromo-3',4'-(methylenedioxy)propiophenone Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-3',4'-(methylenedioxy)propiophenone Suppliers
Global(85)Suppliers
2-Bromo-3',4'-(methylenedioxy)propiophenone Spectrum
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Heterocycles
  • Aromatics
  • 原料
  • 产品
  • PMK 粉末 液体
  • 医药原料
  • 有机中间体
  • 黑色粉末
  • 原料药
  • 化学产品
  • 1-(苯并[D][1,3]二氧杂环戊烯-5-基)-2-溴丙-1-酮
  • PMK 1-(5-苯并[D][1,3]二氧杂环戊烯基)-2-溴丙酮
  • 2-溴-3',4'-(亚甲二氧基)苯丙酮
  • PMK 1-(苯并[D][1,3]二羟基-5-基)-2-溴丙-1-酮
  • 1-(苯并[D][1,3]二氧杂环戊烯-5-基)-2-溴丙烷-1-酮
  • 2-BROMO-3',4'-(METHYLENEDIOXY)
  • 1-(5-苯并[D][1,3]二氧杂环戊烯
  • 1-(5-苯并[D][1,3]二氧杂环戊烯基)-2-溴丙酮
  • 52190-28-0
  • 1-(Benzo [d][1, 3] dioxacyclopentene-5-yl) -2-bromoprop-1-ketone
  • pmk 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one
  • Name 2-Bromo-3',4'-(methylenedioxy)propiophenone
  • Ascorbyl Pa1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-onelmitate
  • Bromo-3′ , 4′ - (methylenedioxy)
  • 1-Propanone, 1-(1,3-benzodioxol-5-yl)-2-bromo-
  • 1-(1,3-benzodioxol-5-yl)-2-bromopropan-1-one
  • 3',4'-Methylenedioxy-α-broMopropiophenone
  • 1-(1,3-Benzodioxol-5-yl)-2-broMo-1-propanone
  • 2-Bromo-3',4'-(methylenedioxy)propiophenone
  • 1-(benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one

Home

My