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Pyrazolo[1,5-a]pyridine

Pyrazolo[1,5-a]pyridine Structure
Pyrazolo[1,5-a]pyridine
  • CAS No.274-56-6
  • Chemical Name:Pyrazolo[1,5-a]pyridine
  • CBNumber:CB6840930
  • Molecular Formula:C7H6N2
  • Formula Weight:118.14
  • MOL File:274-56-6.mol
Pyrazolo[1,5-a]pyridine Property
  • Boiling point 37-39℃/0.2mm
  • Density 1.14±0.1 g/cm3(Predicted)
  • refractive index 1.6075
  • storage temp. Sealed in dry,Room Temperature
  • form Liquid
  • pka 2.83±0.30(Predicted)
  • color Colorless to red or brown
Safety
  • HS Code  :2933399990
  • NFPA 704:
    1
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Pyrazolo[1,5-a]pyridine Chemical Properties,Usage,Production

  • Description Pyrazolo[1,5-a]pyridines, a class of fused heteroaromatic bicyclic compounds, have been investigated for their pharmacological and biological activities. They are used as dopamine D2/D3/D4 antagonists, anti-herpetic agents, p38 kinase inhibitors, PI3 kinase inhibitors, antitubercular agents, EP1 receptor antagonists, 5HT3-antagonists, melatonin receptor (MT1/MT2) ligands, Mcl-1Bcl-xL dual inhibitors, and corticotropin-releasing factor 1 antagonists. Pyrazolo[1,5-a]pyridine has been used as a fluorophore in the research of Zhang et al. and exhibited high quantum yield (0.64, pH 2.4), high selectivity and sensitivity, and extremely short response time[1].
  • References [1] Brian A Johns. “Pyrazolo[1,5-a]pyridines: synthetic approaches to a novel class of antiherpetics.” Tetrahedron 59 45 (2003): Pages 9001-9011.
Pyrazolo[1,5-a]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
Pyrazolo[1,5-a]pyridine Suppliers
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Pyrazolo[1,5-a]pyridine Spectrum
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