Chemical Properties
| form | Liquid |
| color | Colorless to light yellow |
Diridavumab Chemical Properties,Usage,Production
Uses
Diridavumab is a monoclonal anti-HA stalk antibody. Diridavumab stabilizes the prefusion HA structure and prevents pH-dependent fusion of cellular and viral membranes in endosomes. Diridavumab can be used in research of H2 influenza virus[1].in vivo
Diridavumab (CR6261; 1.7-15 mg/kg; i.p.; BALB/c mice with H2 influenza virus) protects mice against lethal H2 influenza virus in a dose-dependent manner[1].
| Animal Model: | BALB/c mice with H2 influenza virus[1] |
| Dosage: | 1.7, 5, or 15 mg/kg |
| Administration: | Intraperitoneal injection |
| Result: | Prevented mortality and decreased the percent weight loss. Decreased viral load, altered antigen distribution, and reduced the severity of airway inflammation. |
References
[1] Sutton TC, et, al. In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice. J Virol. 2017 Nov 30;91(24):e01603-17. DOI:10.1128/JVI.01603-17Diridavumab Suppliers
Global(17)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 027-65317797 15926423062 | 422450190@qq.com | 10300 | 58 | ||
| 177-54423994 17754423994 | 2853530910@QQ.com | 7999 | 62 | ||
| 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | 7353 | 58 | ||
| 15111215862 18229892877 | 3062105966@qq.com | 5580 | 58 | ||
| 15817493340 | 981810490@qq.com | 1577 | 58 | ||
| 027-65279366 18108604356 | products@biolabreagent.com | 9864 | 58 | ||
| 021-65675885 18964387627 | customer_service@efebio.com | 11963 | 58 | ||
| 0573-83568680 18057391398 | 3956524501@qq.com | 1441 | 58 | ||
| 027-87008169 17762441161 | info@atagenix.com | 9997 | 58 | ||
| 18916372613 | yanzihan@shyuanye.com | 87240 | 60 |