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D-Tyrosine

Description References

D-Tyrosine

CAS No.556-02-5
Chemical Name:D-Tyrosine
CBNumber:CB6686592
Molecular Formula:C9H11NO3
Formula Weight:181.19
MOL File:556-02-5.mol

D-Tyrosine Property

Melting point >300 °C (lit.)
Boiling point 314.29°C (rough estimate)
alpha 11.3 º (c=5, 1N HCl)
Density 1.2375 (rough estimate)
refractive index 11.2 ° (C=5, 1mol/L HCl)
storage temp. Store at RT.
solubility Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly)
form Crystals or Powder
pka 2.25±0.10(Predicted)
color White to off-white
optical activity [α]20/D +10.3°, c = 5 in 1 M HCl
Water Solubility SOLUBLE
Merck 14,9839
BRN 2212157
InChIKey OUYCCCASQSFEME-UHFFFAOYSA-N
LogP -0.418 (est)
CAS DataBase Reference 556-02-5(CAS DataBase Reference)
FDA UNII WQ5G9JQ7GC
EPA Substance Registry System D-Tyrosine (556-02-5)
UNSPSC Code 12352209
NACRES NA.22

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36-24/25
WGK Germany :3
TSCA :Yes
HS Code :29225000

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P305+P351+P338

D-Tyrosine Price More Price(9)

Brand: Sigma-Aldrich(India)
Product number: 855456
Product name : D-Tyrosine
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Packaging: 500MG
Price: ₹1948.5
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Brand: Sigma-Aldrich(India)
Product number: 855456
Product name : D-Tyrosine
Purity: ReagentPlus?, 99%
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Brand: TCI Chemicals (India)
Product number: T1141
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Purity:
Packaging: 5G
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Brand: TCI Chemicals (India)
Product number: T1141
Product name : D-Tyrosine
Purity:
Packaging: 25G
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Brand: ottokemi
Product number: T 2260
Product name : D-Tyrosine
Purity: 99%+
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D-Tyrosine Chemical Properties,Usage,Production

Description D-tyrosine is the D-form amino acid of tyrosine. It is a non-essential amino acid. In animals, it can be de novo synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid, hormones and melanin. Specially, study has shown that it can be taken s a chiral precusor to potent inhibitors of human Nonpancreatic secretory phospholipase A 2(IIa) with strong anti-inflammatory activity. It can also be used as a starting material for the preparation of anisomycin.
References https://pubchem.ncbi.nlm.nih.gov/compound/D-tyrosine#section=Top
Dr, Karl A. Hansford, et al. "D -Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A 2, (IIa) with Anti-inflammatory Activity." Chembiochem 4.2-3(2003):181.
Jegham, Samir, and B. C. Das. "A new synthesis of (−)-anisomycin or (+)-anisomycin starting from D-tyrosine or L-tyrosine." Tetrahedron Letters 29.35(1988):4419-4422.
Chemical Properties white to off-white powder
Uses D-Tyrosine is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.
Uses D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic po lypropylene surfaces.
Definition ChEBI: An optically active form of tyrosine having D-configuration.
reaction suitability reaction type: solution phase peptide synthesis