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1-Hydroxy anthraquinone

1-Hydroxy anthraquinone Structure
1-Hydroxy anthraquinone
  • CAS No.129-43-1
  • Chemical Name:1-Hydroxy anthraquinone
  • CBNumber:CB6677576
  • Molecular Formula:C14H8O3
  • Formula Weight:224.21
  • MOL File:129-43-1.mol
1-Hydroxy anthraquinone Property
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H320-H351
  • Precautionary statements P501-P202-P201-P264-P280-P308+P313-P337+P313-P305+P351+P338-P405
1-Hydroxy anthraquinone Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: H0354
  • Product name : 1-Hydroxyanthraquinone
  • Purity: 
  • Packaging: 5G
  • Price: ₹4400
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H0354
  • Product name : 1-Hydroxyanthraquinone
  • Purity: 
  • Packaging: 25G
  • Price: ₹10800
  • Updated: 2022/05/26
  • Buy: Buy

1-Hydroxy anthraquinone Chemical Properties,Usage,Production

  • Uses 1-Hydroxyanthraquinone, a naturally occurring compound with oral activity from some plants like Tabebuia avellanedae, exhibits carcinogenic effect[1].
  • Definition ChEBI: 1-hydroxyanthraquinone is a monohydroxyanthraquinone.
  • Synthesis Reference(s) The Journal of Organic Chemistry, 55, p. 350, 1990 DOI: 10.1021/jo00288a062
  • in vivo

    1-Hydroxyanthraquinone (HA) generates strong DNA repair response and is carcinogenic in rats[1].

    Animal Model:Thirty rats[1].
    Dosage:1% HA in diet.
    Administration:Diet.
    Result:Associated with decreased weight gain which was particularly marked towards the termination of experiment.
    One of the 30 rats in group 1 (experimental group) died of pneumonia 243 days after the start of experiment.
    A second rat died in an unnourished state at day 280, demonstrating a large tumor in the colon.
    Seven animals of the group died spontaneously or were sacrificed upon becoming moribund between 335 and 462 days.
    A total of 21 rats of group 1 survived until the end of experiment (mean value of total intake of HA/rat was 76.8 g).
  • References [1] H Mori, et al. Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: induction of large bowel, liver and stomach neoplasms. Carcinogenesis. 1990 May;11(5):799-802. DOI:10.1093/carcin/11.5.799
1-Hydroxy anthraquinone Preparation Products And Raw materials
Raw materials
Preparation Products
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1-Hydroxy anthraquinone Spectrum
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