Synthesis
ChemicalBook > CAS DataBase List > 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile

Synthesis
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Structure
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
  • CAS No.93413-76-4
  • Chemical Name:2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
  • CBNumber:CB6476117
  • Molecular Formula:C15H19NO2
  • Formula Weight:245.32
  • MOL File:93413-76-4.mol
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Property
  • Melting point 121-123°C
  • Boiling point 410.1±25.0 °C(Predicted)
  • Density 1.142±0.06 g/cm3(Predicted)
  • storage temp. Sealed in dry,2-8°C
  • solubility soluble in Methanol
  • form powder to crystal
  • pka 13.80±0.20(Predicted)
  • color White to Almost white
  • CAS DataBase Reference 93413-76-4(CAS DataBase Reference)
Safety
  • HS Code  :2926.90.4850
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302+H312+H332-H315-H319
  • Precautionary statements P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: H1303
  • Product name : (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile
  • Purity: 
  • Packaging: 1G
  • Price: ₹7300
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H1303
  • Product name : (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile
  • Purity: 
  • Packaging: 5G
  • Price: ₹16700
  • Updated: 2022/05/26
  • Buy: Buy

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Chemical Properties,Usage,Production

  • Synthesis A mixture of p-methoxyphenylacetonitrile 36 (100 g, 0.68 mol), 10% aqueous NaOH solution (100 ml, 0.25 mol) and TBAHSO4 (5 g, 0.014 mol) was stirred at room temperature for 30 minutes. A dark red colour appeared. To this was added cyclohexanone 34 (67 g, 0.680 mol) in small portions at 0 ºC, with vigorous stirring, in such a way that temperature should not rise above 10 ºC. A white solid was formed within 30 minutes to one hour. The solid was crushed and the reaction mixture was further stirred vigorously at room temperature for one more hour. The solid was filtered, washed with water till neutral to pH paper and air-dried. Crystallization from ethyl acetatepetroleum ether (500:350, v/v) gave a bright white solid (161.66 g).
  • Chemical Properties White Powder
  • Uses An intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Spectrum
93413-76-4, 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)AcetonitrileRelated Search:
  • (intermediate of venlafaxine hcl)
  • (intermediate of venlafaxine)
  • API intermediates
  • Nitriles
  • Medicine intermediate
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • 杂质对照品
  • 高端化学
  • 化工中间体
  • 氰化物
  • 腈
  • 医药原料和中间体
  • 盐酸文拉法辛中间体
  • C15H19O2N
  • 文拉法辛杂质3(文拉法辛羟基腈杂质)
  • 文拉法辛氰基杂质(文拉法辛杂质23)
  • 文拉法辛杂质28
  • 2-(1-羟基环己基)-2-(4-甲氧基苯基)乙腈
  • 文拉法辛杂质3(文拉法辛羟基丁腈杂质)
  • 文拉法辛氰杂质
  • 文拉法辛氰基杂质
  • 文拉法辛羟基腈杂质
  • 1-羟环己基)(4-甲氧基苯基)乙腈
  • 文拉法辛含氰基杂质
  • 1-羟基环己基-4-甲氧基苯乙腈
  • 1-羟基环己基-4-甲氧基乙腈
  • 93413-76-4
  • 1-(4-Methoxyphenyl)-2-(1-hydroxycyclohexyl)acetonitrile
  • 1-(4-Methoxyphenyl)-4-hydroxycyclohexanecarbonitrile
  • VENLAFAXINE CYNO IMPURITY
  • Effexor Impurity 28
  • (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile, ≥ 98.0%
  • Venlafaxine Cyano
  • 1-[Cyano-(4-methoxyphenyl)methyl] cyclohexanol (VENLA-I)
  • 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
  • 2-(1-Hydroxycyclohexyl)-2-(4-methoxypheny)acetonitrile
  • Venlafaxine Impurity 28
  • 1- [Cyano (P- Methoxyphenyl) Methyl] Cyclohexanol: VNF Stage-I
  • 1-(HYDROXYCYCLOHEXY)-(4-METHOXYPHENLY)ACETONITRLLE
  • Benzeneacetonitrile, α-(1-hydroxycyclohexyl)-4-methoxy-
  • (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile&gt
  • Venlafaxine Impurity 15
  • 3-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)propanenitrile
  • D,L-VENLAFAXINE, HYDROCHLORIDE int
  • Venlafaxine Impurity 3 (Venlafaxine Hydroxy Nitrile Impurity)
  • Venlafaxine Nitrile Impurity
  • Venlafaxine hydroxynitrile impurities
  • 1-(CYANO-(4-METHOXY PHENYL) METHYL) CYCLOHEXANOL
  • 1-[CYANO-(P-METHOXYPHENYL)METHYL]CYCLOHEXANOL
  • 1-[(1-CYANO)-1-(4-METHOXYPHENYL)METHYL] CYCLOHEXANOL
  • Venlafaxine Cyano Impurity
  • Venlafaxine Hydroxy Nitrile Impurity
  • α-(p-Methoxyphenyl)-α-(1-hydroxycyclohexyl)acetonitrile
  • α-(1-Hydroxycyclohexyl)-4-Methoxy-benzeneacetonitrile
  • 1-(p-Methoxyphenyl-cyano)-methylcyclohexanol
  • 4-Methoxy benzyl cyano cyclohexanol
  • 1-[CYANO-(4-METHOXYPHENYL)METHYL]CYCLOHEXANOL[FOR VENLAFAXINE HCL]

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