Uses
2, 3-Dinor Thromboxane B2-d9 serves as an internal standard for the quantification of 2,3-Dinor TXB2. 2, 3-Dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker in vivo TXA2 synthesis.
References
[1] GIOVANNI CIABATTONI . Fractional conversion of thromboxane B2 to urinary 11-dehydrothromboxane B2 in man[J]. Biochimica et biophysica acta. General subjects, 1989, 992 1: Pages 66-70. DOI:
10.1016/0304-4165(89)90051-2[2] JOHN A. LAWSON. Measurement of urinary 2,3-dinor-thromboxane B2 and thromboxane B2 using bonded-phase phenylboronic acid columns and capillary gas chromatography-negative-ion chemical ionization mass spectrometry[J]. Analytical biochemistry, 1985, 150 2: Pages 463-470. DOI:
10.1016/0003-2697(85)90536-6[3] JOHN A. LAWSON . Long-lived enzymatic metabolites of thromboxane B2 in the human circulation[J]. Analytical biochemistry, 1986, 155 1: Pages 198-205. DOI:
10.1016/0003-2697(86)90247-2[4] JIE YANG. Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity[J]. Nature, 2025, 640 8060: 1052-1061. DOI:
10.1038/s41586-025-08626-7
