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(R)-N-Boc-3-pyrrolidineacetic acid

(R)-N-Boc-3-pyrrolidineacetic acid Structure
(R)-N-Boc-3-pyrrolidineacetic acid
  • CAS No.204688-60-8
  • Chemical Name:(R)-N-Boc-3-pyrrolidineacetic acid
  • CBNumber:CB6409081
  • Molecular Formula:C11H19NO4
  • Formula Weight:229.27
  • MOL File:204688-60-8.mol
(R)-N-Boc-3-pyrrolidineacetic acid Property
  • Boiling point 357.4±15.0 °C(Predicted)
  • Density 1.151±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • pka 4.65±0.10(Predicted)
Safety
  • Hazard Codes  :T,N
  • Risk Statements  :25-50
  • Safety Statements  :45-61
  • RIDADR  :UN2811
  • HS Code  :2933998090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319
  • Precautionary statements P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

(R)-N-Boc-3-pyrrolidineacetic acid Chemical Properties,Usage,Production

  • Synthesis (R)-N-Boc-3-pyrrolidineacetic acid is synthesised using Di-tert-butyl dicarbonate as raw material by chemical reaction. The specific synthesis steps are as follows:
    A solution of 4.95 g of the preceding step product in 50 ml of dichloromethane and 25 ml of trifluoroacetic acid is stirred at room temperature for 3 h. and concentrated. The residue is dissolved in 40 ml of dioxan and 40 ml of 1N NaOH, treated at room temperature with 4.3 g of di-tert-butyl dicarbonate in 40 ml of dioxan and stirred for 1.5 h. The reaction mixture is diluted with ether, the organic phase is washed with 1N NaOH and the aqueous phase is acidified with 3N HCl. Extraction of the aqueous phase with ether, washing, drying and concentration of the ether phase gives 0.72 g of tert-butyl(R)-3-carboxymethyl-pyrrolidine-1-carboxylate.
    (R)-N-Boc-3-pyrrolidineacetic acid synthesis
(R)-N-Boc-3-pyrrolidineacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-N-Boc-3-pyrrolidineacetic acid Suppliers
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(R)-N-Boc-3-pyrrolidineacetic acid Spectrum
204688-60-8, (R)-N-Boc-3-pyrrolidineacetic acidRelated Search:
  • pharmacetical
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  • 204688-60-8
  • (R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid
  • (R)-3-carboxymethyl-pyrrolidin-1-carboxylic acid tert-butyl ester
  • 2-[(3R)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]acetic acid
  • (R)-1-tert-Butoxycarbonylpyrrolidine-3-acetic acid
  • 2-[(3S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]acetic acid
  • N-BOC-(R)-pyrrolidin-3-acetic acid
  • 3-Pyrrolidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, (3R)-
  • (3R)-1-Boc-3-pyrrolidineacetic acid
  • (R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid
  • (R)-1-N-Boc-3-pyrrolidineacetic acid
  • (R)-N-BOC-3-PYRROLIDINEACETIC ACID
  • (R)-N-BOC-PYRROLIDINE-3-ACETIC ACID
  • (R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID
  • (R)-3-CARBOXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 2-[(3R)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl]acetic acid
  • (R)-N-Boc-3-(R)-(1-Boc-Pyrrolidin-3-yl)-aceticacid
  • (R)-1-Boc-3-pyrrolidineacetic acid

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