ChemicalBook > CAS DataBase List > 1-Hydroxy-2-naphthoic acid

1-Hydroxy-2-naphthoic acid

CAS No.86-48-6
Chemical Name:1-Hydroxy-2-naphthoic acid
CBNumber:CB6317591
Molecular Formula:C11H8O3
Formula Weight:188.18
MOL File:86-48-6.mol

1-Hydroxy-2-naphthoic acid Property

Melting point 195-200 °C (dec.) (lit.)
Boiling point 283.17°C (rough estimate)
Density 1.2100 (rough estimate)
refractive index 1.6310 (estimate)
Flash point 150 °C
storage temp. Sealed in dry,Room Temperature
solubility alcohol: freely soluble
form Powder or Crystals
pka 3.02±0.30(Predicted)
color White to slightly pink to tan
Water Solubility SOLUBLE IN HOT WATER
Merck 14,4834
BRN 974438
InChIKey SJJCQDRGABAVBB-UHFFFAOYSA-N
LogP 3.196 (est)
CAS DataBase Reference 86-48-6(CAS DataBase Reference)
FDA UNII U8LZ3R07L8
EPA Substance Registry System 1-Hydroxy-2-naphthoic acid (86-48-6)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36-37/39-37
WGK Germany :3
TSCA :Yes
HS Code :29182910

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338

1-Hydroxy-2-naphthoic acid Price More Price(8)

Brand: Sigma-Aldrich(India)
Product number: 109630
Product name : 1-Hydroxy-2-naphthoic acid
Purity: ≥97.0%
Packaging: 5G
Price: ₹1937.68
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 109630
Product name : 1-Hydroxy-2-naphthoic acid
Purity: ≥97.0%
Packaging: 100G
Price: ₹2338.2
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: H0279
Product name : 1-Hydroxy-2-naphthoic Acid
Purity:
Packaging: 25G
Price: ₹2800
Updated: 2022/05/26
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Brand: ALFA India
Product number: ALF-A12785-36
Product name : 1-Hydroxy-2-naphthoic acid, 98+%
Purity:
Packaging: 500g
Price: ₹3361
Updated: 2022/05/26
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Brand: TCI Chemicals (India)
Product number: H0279
Product name : 1-Hydroxy-2-naphthoic Acid
Purity:
Packaging: 100G
Price: ₹5200
Updated: 2022/05/26
Buy: Buy

1-Hydroxy-2-naphthoic acid Chemical Properties,Usage,Production

Chemical Properties beige to brown-grey powder. 1-Hydroxy-2-naphthoic acid [86-48-6], C11H8O3, Mr 188.17, mp 200℃, is only sparingly soluble in hot water but readily soluble in alkali and ethanol. It couples with diazo compounds in the 4-position and, with excess, in the 4,7-positions. It is sulfonated by oleum to give the 4-sulfonic and then the 4,7-disulfonic acids. Halogenation occurs in the 4-position, and nitrosation gives 2-nitroso-1-naphthol.
Uses Metabolite from phenanthrene degradation. 1-Hydroxy-2-naphthoic acid is used as an intermediate for azo and triphenylmethane dyes and, more recently, for color-film dyes.
Uses It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
Definition ChEBI: 1-hydroxy-2-naphthoic acid is a naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. It has a role as a bacterial xenobiotic metabolite and a fungal xenobiotic metabolite. It is a naphthoic acid, a member of naphthols and a hydroxy monocarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a 1-hydroxy-2-naphthoate.
Preparation Treatment of the dried sodium salt of 1-naphthol with carbon dioxide at 135℃ under pressure gives an 80 % yield of product.
General Description 1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.
Purification Methods Successively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.]