Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the dried rhizome of Acanthopanax senticosus.
Uses
CiwujianosideC3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanaxhenryi Harms. CiwujianosideC3 has anti-inflammatory effect and can reinforces object recognition memory[1][2].
in vivo
| Animal Model: | Mice[1] |
| Dosage: | 0.5 mg/kg |
| Administration: | Oral administration; 0.5 mg/kg/day; 17 days |
| Result: | Reinforced object recognition memory. |
References
[1] Kang DH, et al. Anti-inflammatory effects of Ciwujianoside C3, extracted from the leaves of Acanthopanax henryi (Oliv.) Harms, on LPS-stimulated RAW 264.7 cells. Mol Med Rep. 2016 Oct;14(4):3749-58. DOI:
10.3892/mmr.2016.5710[2] Yamauchi Y, et al. Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain.Nutrients. 2019 May 22;11(5). DOI:
10.3390/nu11051142
