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N33-TEG-COOH

Uses
N33-TEG-COOH Structure
N33-TEG-COOH
  • CAS No.201467-81-4
  • Chemical Name:N33-TEG-COOH
  • CBNumber:CB62755924
  • Molecular Formula:C10H19N3O6
  • Formula Weight:277.28
  • MOL File:201467-81-4.mol
N33-TEG-COOH Property
  • Density 0.750-0.850 g/mL at 20 °C
  • Flash point -33℃
  • storage temp. 2-8°C
  • form Liquid
  • color Colorless to light yellow
  • BRN 7928855
  • UNSPSC Code 12352106
  • NACRES NA.22
Safety
  • Hazard Codes  :F,Xi
  • Risk Statements  :11-38
  • Safety Statements  :16
  • RIDADR  :UN 2398 3 / PGII
  • WGK Germany  :2
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H315
  • Precautionary statements P210
N33-TEG-COOH Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 744751
  • Product name : 14-Azido-3,6,9,12-tetraoxatetradecanoic acid solution
  • Purity: ~0.5?M in tert-butyl methyl ether, ≥90% (HPLC)
  • Packaging: 500MG
  • Price: ₹5852
  • Updated: 2022/06/14
  • Buy: Buy

N33-TEG-COOH Chemical Properties,Usage,Production

  • Uses Azido-PEG4-CH2CO2H is a useful research chemical.
  • Description Azido-PEG4-CH2CO2H is a very popular click chemistry linker containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU).
  • Uses N33-TEG-COOH (N3-TEG-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. N33-TEG-COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • reaction suitability reaction type: click chemistry
    reagent type: linker
  • IC 50 PEGs
  • References [1] Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. DOI:10.1021/acschembio.5b00216
N33-TEG-COOH Preparation Products And Raw materials
Raw materials
Preparation Products
N33-TEG-COOH Suppliers
Global(62)Suppliers
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N33-TEG-COOH Spectrum
  • peg
  • 高端化学
  • 其它
  • 分析试剂
  • C10H19N3O6
  • 叠氮-PEG4-CH2COOH
  • 14-叠氮-3,6,9,12-四氧杂十四烷酸
  • 叠氮基-PEG4-CH2CO2H
  • 14-叠氮基-3,6,9,12-四氧杂十四烷酸 溶液
  • 叠氮-四聚乙二醇-乙酸
  • 14-叠氮基-3,6,9,12-四氧杂十四烷酸
  • 叠氮-PEG4-乙酸
  • 叠氮-四聚乙二醇-乙酸,AZIDO-PEG4-CH2CO2H
  • 叠氮四聚乙二醇羧甲基
  • 201467-81-4
  • 4-Azido-3,6,9,12-tetraoxatetradecanoic acid solution
  • 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]acetic acid
  • Azido-PEG4-acetic acid
  • 14-azido-3,6,9,12-tetraoxa-1-tetradecanoic acid
  • N3-TEG-COOH
  • 14-Azido-3,6,9,12-tetraoxatetradecanoic acid
  • 14-Azido-3,6,9,12-tetraoxatetradecanoic acid solution - 0.5M solution in tert-butyl methyl ether
  • Acetic acid, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-
  • N3-PEG4-CH2COOH
  • 14-Azido-3,6,9,12-tetraoxatetradecanoic acid solution ~0.5 M in tert-butyl methyl ether, >=90% (HPLC)
  • N33-TEG-COOH
  • 2-{2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethoxy}acetic acid solution
  • 14-Azido-3,6,9,12-tetraoxatetradecanoic acid solution

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