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tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Structure
tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • CAS No.1628047-84-6
  • Chemical Name:tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • CBNumber:CB62750116
  • Molecular Formula:C18H17BrN2O3
  • Formula Weight:389.24
  • MOL File:1628047-84-6.mol
tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Property
  • Melting point 188 - 190°C
  • Density 1.445±0.06 g/cm3(Predicted)
  • storage temp. -20°C Freezer, Under inert atmosphere
  • solubility Chloroform (Slightly), DMSO (Slightly)
  • pka 13.26±0.40(Predicted)
  • form Solid
  • color White to Off-White
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Chemical Properties,Usage,Production

  • Uses tert-?Butyl 4-?Bromo-?2-?(1H-?pyrrolo[2,?3-?b]?pyridin-?5-?yloxy)benzoate is used in the synthesis of apoptosis-inducing agents. Intermediate of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets.
tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Preparation Products And Raw materials
Raw materials
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tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Spectrum
1628047-84-6, tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoateRelated Search:
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  • ABT199 intermediate 2
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  • tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

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