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Heterophyllin B

Heterophyllin B Structure
Heterophyllin B
  • CAS No.145459-19-4
  • Chemical Name:Heterophyllin B
  • CBNumber:CB62604877
  • Molecular Formula:C40H58N8O8
  • Formula Weight:778.94
  • MOL File:145459-19-4.mol
Heterophyllin B Property
  • Boiling point 1159.7±65.0 °C(Predicted)
  • Density 1.29±0.1 g/cm3 (20 ºC 760 Torr)
  • storage temp. 4°C, protect from light
  • solubility Soluble in DMSO
  • pka 13.44±0.70(Predicted)
  • form Solid
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Heterophyllin B Chemical Properties,Usage,Production

  • Chemical Properties White crystal, easily soluble in methanol, derived from Radix Radix.
  • Uses Taizishencyclopeptide B has the functions of invigorating qi and blood, invigorating body fluid and invigorating the spleen and stomach. And it was used for content determination/identification/pharmacological experiments, etc.
  • Biological Activity Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. It can be used in esophageal cancer research.
  • in vitro

    Heterophyllin B (0-200 μM; 12-48 hours) reduces cell viability in the 75, 100 and 200 μM groups, has no effect on 5, 10, 25 and 50 μM groups.Heterophyllin B (0 -50 μM; 6 hours) suppresses the expression levels of p-PI3K, p-AKT and β-catenin in a dose-dependent manner in ECA-109 cells.

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    Cell Viability Assay

    Cell Line: ECA-109 cells
    Concentration: 5 μM, 10 μM, 25 μM, 50 μM, 75 μM, 100 μM and 200 μM
    Incubation Time: 12, 24 and 48 hours
    Result: Decrease cell viability at high concentrations.

    Western Blot Analysis

    Cell Line: ECA-109 cells
    Concentration: 0 μM, 10 μM, 25 μM, 50 μM
    Incubation Time: 6 hours
    Result: Decreased the phosphorylation of PI3K/AKT and the expression of β-catenin.
Heterophyllin B Preparation Products And Raw materials
Raw materials
Preparation Products
Heterophyllin B Suppliers
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Heterophyllin B Spectrum
145459-19-4, Heterophyllin BRelated Search:
  • standard substance
  • reagent
  • 抑制剂
  • 中药标准品，对照品
  • 药靶配体
  • 目录肽
  • 标准品，对照品
  • 标准品 -中药标准品
  • 对照品-中药对照品
  • 植物提取物
  • 标准品
  • 对照品
  • 中药对照品
  • C40H58N8O8
  • 太子参环肽B/HPLC
  • 异黄酮B
  • 标准品对照品】HETEROPHYLLIN B
  • (6S,15S,18S,20AS,25AS,30AS)-15-苄基-18-((S)-仲丁基)-6-异丁基二十氢-1H,25H-三吡咯并[1,2-A:1',2'-D:1'',2''-G][1,4,7,10,13,16,19,22]八氮杂环二十四烷-5,8,11,14,17,20,25,30(30AH)-八酮
  • 太子参环肽B对照品
  • 145459-19-4
  • (6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone
  • Cyclo(glycylglycyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-isoleucyl-L-phenylalanyl)
  • Cyclo(glycylglycyl-L-isoleucyl-L-prolyl-L-prolyl-L-prolyl-L-isole ucyl-L-phenylalanyl)
  • Prince Ginseng Cyclic Peptide B
  • Heterophylin B
  • Heterophyllin B

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