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(S)-Ketorolac

(S)-Ketorolac Structure
(S)-Ketorolac
  • CAS No.66635-92-5
  • Chemical Name:(S)-Ketorolac
  • CBNumber:CB62485724
  • Molecular Formula:C15H13NO3
  • Formula Weight:255.27
  • MOL File:66635-92-5.mol
(S)-Ketorolac Property
  • Melting point 160-167?C
  • Boiling point 493.2±40.0 °C(Predicted)
  • Density 1.33±0.1 g/cm3(Predicted)
  • storage temp. Refrigerator
  • solubility Chloroform: Slightly; Ethanol: >1mg/ml; Methanol: Slightly
  • form A crystalline solid
  • pka 4.29±0.20(Predicted)
  • color White to off-white
  • optical activity [α]/D -165 to -185°, c =0.5 in methanol
  • FDA UNII 5H3TJ0A81K
  • UNSPSC Code 51111800
  • NACRES NA.77
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301
  • Precautionary statements P264-P270-P301+P310-P405-P501
(S)-Ketorolac Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: SML3299
  • Product name : S-Ketorolac
  • Purity: ≥98% (HPLC)
  • Packaging: 5MG
  • Price: ₹11106.45
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: SML3299
  • Product name : S-Ketorolac
  • Purity: ≥98% (HPLC)
  • Packaging: 25MG
  • Price: ₹44728.9
  • Updated: 2022/06/14
  • Buy: Buy

(S)-Ketorolac Chemical Properties,Usage,Production

  • Description (S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). (S)-Ketorolac is approximately twice as potent as the racemic mixture and 60 times more potent than (R)-ketorolac in a rat pain assay. (S)-Ketorolac is cleared from rat kidney and liver more quickly than (R)-ketorolac. Formulations containing ketorolac have been used to manage postoperative pain as well as an ophthalmic solution to treat ocular pain and inflammation.
  • Chemical Properties Off-White Solid
  • Uses The R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
  • Uses (S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
  • Definition ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known s mply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
(S)-Ketorolac Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-Ketorolac Suppliers
Global(67)Suppliers
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(S)-Ketorolac Spectrum
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  • (S)-Ketorolac ISO 9001：2015 REACH
  • 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1S)-
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