ChemicalBook > CAS DataBase List > CP 31398
CP 31398
CP 31398
- CAS No.259199-65-0
- Chemical Name:CP 31398
- CBNumber:CB62458908
- Molecular Formula:C22H26N4O
- Formula Weight:362.47
- MOL File:259199-65-0.mol
CP 31398 Property
- RTECS TX8230000
- storage temp. Desiccate at RT
- form Yellow solid
- FDA UNII IN3WH41H3A
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302
- Precautionary statements P264b-P270-P301+P312-P330-P403-P501c
CP 31398 Chemical Properties,Usage,Production
- Uses CP-31398 is reported to restore p53 activity in mutant cells.
- Biological Activity p53 stabilizing agent. Stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Inhibits growth of small human tumor xenografts in vivo .
-
in vivo
CP-31398 (100 mg/kg, orally, twice daily for 7 days) exhibits significant anti-tumor activity in mice models[1]
Animal Model: Small human tumor xenografts in mice[1] Dosage: 100 mg/kg Administration: Orally twice daily for 7 days Result: Suppressed A375.S2 tumor growth by -50%.
CP 31398 Preparation Products And Raw materials
Raw materials
Preparation Products
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259199-65-0, CP 31398Related Search:
- C22H26N4OHCl
- CP-31398 DIHYDROCHLORIDE,P53 STABILIZING AGENT
- N3-[2-(4-甲氧基苯基)乙烯基]-4-喹唑啉基]-N1,N1-二甲基-1,3-丙二胺
- 259199-65-0
- CP-31398 dihydrochloride, p53 stabilizing agent
- 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-
- p53 Modulator, CP-31398 - CAS 259199-65-0 - Calbiochem
- CP 31398 2HCl
- N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediaminedihydrochloride
- CP 31398 dihydrochloride
- CP 31398