ChemicalBook > CAS DataBase List > 1-Aminonaphthalene-6-sulfonic acid

1-Aminonaphthalene-6-sulfonic acid

CAS No.119-79-9
Chemical Name:1-Aminonaphthalene-6-sulfonic acid
CBNumber:CB6228406
Molecular Formula:C10H9NO3S
Formula Weight:223.25
MOL File:119-79-9.mol

1-Aminonaphthalene-6-sulfonic acid Property

Melting point >300°C
Density 1.3588 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.6500 (estimate)
storage temp. Refrigerator
solubility soluble100mg/mL, clear, brown (1N NH4OH)
pka pK1: 3.80 (25°C)
form Solid
color Purple
Water Solubility 1g/L(16 ºC)
Merck 14,2350
BRN 1819887
Dissociation constant 0 at 39℃
CAS DataBase Reference 119-79-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 59G56TB11B
NIST Chemistry Reference 1-Naphthylamine-6-sulfonic acid(119-79-9)
EPA Substance Registry System 2-Naphthalenesulfonic acid, 5-amino- (119-79-9)
UNSPSC Code 12352100
NACRES NA.22

Safety

Risk Statements :36/37/38
Safety Statements :26-36/37/39-24/25
RIDADR :1759
WGK Germany :1
RTECS :QK1285000
TSCA :Yes
HazardClass :8
PackingGroup :III
HS Code :29309090

NFPA 704:

	0
0		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319
Precautionary statements P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

1-Aminonaphthalene-6-sulfonic acid Price More Price(8)

Brand: Sigma-Aldrich(India)
Product number: 285072
Product name : 5-Amino-2-naphthalenesulfonic acid
Purity: ≥95%
Packaging: 5G
Price: ₹2035.1
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 285072
Product name : 5-Amino-2-naphthalenesulfonic acid
Purity: ≥95%
Packaging: 100G
Price: ₹7988.85
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: A0346
Product name : 5-Amino-2-naphthalenesulfonic Acid
Purity:
Packaging: 25G
Price: ₹2400
Updated: 2022/05/26
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Brand: ALFA India
Product number: ALF-L03099-14
Product name : 5-Aminonaphthalene-2-sulfonic acid, 97%
Purity:
Packaging: 25g
Price: ₹2105
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: A0346
Product name : 5-Amino-2-naphthalenesulfonic Acid
Purity:
Packaging: 500G
Price: ₹6900
Updated: 2022/05/26
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1-Aminonaphthalene-6-sulfonic acid Chemical Properties,Usage,Production

Chemical Properties Purple Solid. 1-Aminonaphthalene-6-sulfonic acid [119- 79-9]. (5-aminonaphthalene-2-sulfonic acid), 1,6-Cleve’s acid, C10H9NO3S, Mr 223.24, crystallizes from boiling water as plates of the dihydrate. Its sodium, potassium, and calcium salts are all readily soluble in water, but the barium salt is only sparingly soluble. Sulfonation with 10 % oleum yields 1-aminonaphthalene-4,6-disulfonic acid. Caustic fusion gives 5- amino-2-hydroxynaphthalene, and Bucherertype hydrolysis gives 1-hydroxynaphthalene-6- sulfonic acid.
Uses Intermediate of dyestuff
Uses 5-Amino-2-naphthalenesulfonic acid (1,6-Cleve′s acid) was used in the synthesis of nitrate reductase and detection of nitrate reduction by anaerobic bacteria.
Uses Fluorescent reagent.
Definition ChEBI: 5-aminonaphthalene-2-sulfonic acid is an aminonaphthalenesulfonic acid.
Production Methods Sulfonation of 1-naphthylamine with concentrated sulfuric acid at 130℃ gives mainly 1-aminonaphthalene-6-sulfonic acid. However, the latter is always made, together with the 1,7-isomer, by nitration of naphthalene-2-sulfonic acid to give the mixed 5- and 8- nitronaphthalene-2-sulfonic acids follwed by reduction to ‘‘mixed Cleve’s acids.’’ A b-sulfonation mass is diluted with sulfuric acid, then 67.5 % nitric acid is added slowly at 34℃. After being quenched and neutralized with calcium carbonate, the filtered liquor is reduced by boiling with iron powder, slight acidity being maintained with sulfuric acid. After basification with magnesia the iron residues are filtered off and the filtrate is evaporated until the magnesium salt of the product crystallizes on cooling. Filtration followed by washing with magnesium sulfate gives a 34 % yield of the magnesium salt of 1,6-Cleve’s acid. Purification by dissolution in hot water, acidification, and filtration of the free acid while hot reduce the yield to 25 % based on naphthalene.
General Description The crystal structure of 5-amino-2-naphthalenesulfonic acid (1,6-Cleve′s acid) depicted the presence of a sulfonate-aminium group zwitterion.