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2-Methoxy-5-methylaniline

CAS No.120-71-8
Chemical Name:2-Methoxy-5-methylaniline
CBNumber:CB6191898
Molecular Formula:C8H11NO
Formula Weight:137.18
MOL File:120-71-8.mol

2-Methoxy-5-methylaniline Property

Melting point 50-52 °C (lit.)
Boiling point 235 °C (lit.)
Density 1.0252 (rough estimate)
vapor density 4.7 (vs air)
vapor pressure 2.6Pa at 20℃
refractive index 1.5647 (estimate)
Flash point >230 °F
storage temp. Room Temperature, under inert atmosphere
solubility Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)
pka 4.66±0.10(Predicted)
form Crystalline Chunks
color Brown to black
Water Solubility Slightly soluble in hot water.
BRN 637071
Stability Air Sensitive
InChIKey WXWCDTXEKCVRRO-UHFFFAOYSA-N
LogP 1.65 at 23℃ and pH7
CAS DataBase Reference 120-71-8(CAS DataBase Reference)
EWG's Food Scores 3
FDA UNII 4C11L78UR3
Proposition 65 List p-Cresidine
IARC 2B (Vol. 27, Sup 7) 1987
NIST Chemistry Reference Benzenamine, 2-methoxy-5-methyl-(120-71-8)
EPA Substance Registry System p-Cresidine (120-71-8)
UNSPSC Code 41116107
NACRES NA.24

Safety

Hazard Codes :T,Xi
Risk Statements :45-22
Safety Statements :53-45
WGK Germany :3
RTECS :BZ6720000
F :9
HazardClass :IRRITANT
HS Code :29222990
Hazardous Substances Data :120-71-8(Hazardous Substances Data)
Toxicity :rat,LD50,oral,1450mg/kg (1450mg/kg),Huntingdon Research Center Reports. Vol. -, Pg. -, 1972.

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H302-H319-H350
Precautionary statements P201-P301+P312+P330-P305+P351+P338-P308+P313

2-Methoxy-5-methylaniline Price More Price(5)

Brand: Sigma-Aldrich(India)
Product number: 46111
Product name : 2-Methoxy-5-methylaniline
Purity: analytical standard
Packaging: 250MG
Price: ₹2002.63
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 103284
Product name : 2-Methoxy-5-methylaniline
Purity: 99%
Packaging: 100G
Price: ₹9417.75
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 103284
Product name : 2-Methoxy-5-methylaniline
Purity: 99%
Packaging: 500G
Price: ₹29844.53
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: M0115
Product name : 2-Methoxy-5-methylaniline
Purity: min. 98.0 %
Packaging: 25G
Price: ₹2000
Updated: 2022/05/26
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Brand: TCI Chemicals (India)
Product number: M0115
Product name : 2-Methoxy-5-methylaniline
Purity: min. 98.0 %
Packaging: 500G
Price: ₹14900
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2-Methoxy-5-methylaniline Chemical Properties,Usage,Production

Description p-Cresidine is a white crystalline solid.Molecular weight =137.20. Boiling point =235℃;Freezing/Melting point = 52℃; Flash point $ 112℃;Autoignition temperature =450℃. Hazard Identification(based on NFPA-704 M Rating System): Health 2,Flammability 1, Reactivity 0. Practically insoluble in water.
Chemical Properties brown to black crystalline chunks
Chemical Properties p-Cresidine is a white crystalline solid.
Uses p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides. Dyes and metabolites, Environmental Testing.
Uses 2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase.
Definition ChEBI: Para-Cresidine is a member of methoxybenzenes.
General Description White to silver-gray odorless crystals.
Air & Water Reactions Insoluble in water.
Reactivity Profile 2-Methoxy-5-methylaniline is sensitive to moisture and temperatures greater than 104°F. Incompatible with strong oxidizing agents .
Hazard A possible carcinogen.
Fire Hazard 2-Methoxy-5-methylaniline is nonflammable.
Safety Profile Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Moderately toxic by ingestion. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.
Potential Exposure p-Cresidine is used as an intermediate in the production of various azodyes, printing inks, and pigments; including 11 dyes that are produced commercially in the United States. Human exposure to p-Cresidine occurs primarily through inhalation of
First aid If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Note to physician: Treat for methemoglobinemia.Spectrophotometry may be required for precise determination of levels of methemoglobinemia in urine.
Carcinogenicity p-Cresidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
storage Color Code—Blue (potential carcinogen): HealthHazard/Poison: Store in a secure poison location. Prior toworking with this chemical you should be trained on itsproper handling and storage. Before entering confined spacewhere this chemical may be present, check to make surethat an explosive concentration does not exist. Store intightly closed containers in a cool, well-ventilated areaaway from oxidizers. Store in a refrigerator under an inertatmosphere for prolonged storage. A regulated, marked areashould be established where this chemical is handled, used,or stored in compliance with OSHA Standard 1910.1045.
Shipping UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required
Incompatibilities Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.