ChemicalBook > CAS DataBase List > Dextromethorphan hydrobromide monohydrate

Dextromethorphan hydrobromide monohydrate

Dextromethorphan hydrobromide monohydrate Structure
Dextromethorphan hydrobromide monohydrate
  • CAS No.6700-34-1
  • Chemical Name:Dextromethorphan hydrobromide monohydrate
  • CBNumber:CB6131946
  • Molecular Formula:C18H28BrNO2
  • Formula Weight:370.33
  • MOL File:6700-34-1.mol
Dextromethorphan hydrobromide monohydrate Property
  • Melting point 116-119°C
  • alpha [α]D25 +26～+30° (c=1.85, H2O)
  • Flash point 11 °C
  • storage temp. Store at RT
  • solubility Sparingly soluble in water, freely soluble in ethanol (96 per cent).
  • form solid
  • color White to Off-White
  • PH pH (10g/l, 25℃) : 5.2～6.5
  • BRN 6453793
  • InChIKey QYPSYPPSHXDFLV-UHFFFAOYSA-N
  • LogP 1.351 (est)
  • CAS DataBase Reference 6700-34-1(CAS DataBase Reference)
  • FDA UNII 9D2RTI9KYH
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301-H411
  • Precautionary statements P264-P270-P273-P301+P310-P391-P405
Dextromethorphan hydrobromide monohydrate Price More Price(7)
  • Brand: Sigma-Aldrich(India)
  • Product number: D9684
  • Product name : Dextromethorphan hydrobromide
  • Purity: meets USP testing specifications
  • Packaging: 10G
  • Price: ₹10240.45
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D9684
  • Product name : Dextromethorphan hydrobromide
  • Purity: meets USP testing specifications
  • Packaging: 5G
  • Price: ₹10370.35
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: PHR1018
  • Product name : Dextromethorphan HBr
  • Purity: certified reference material, pharmaceutical secondary standard
  • Packaging: 500MG
  • Price: ₹9493.53
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D9684
  • Product name : Dextromethorphan hydrobromide
  • Purity: meets USP testing specifications
  • Packaging: 50G
  • Price: ₹33622.45
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D2531
  • Product name : Dextromethorphan hydrobromide monohydrate
  • Purity: ≥99% (TLC)
  • Packaging: 5G
  • Price: ₹7425.95
  • Updated: 2022/06/14
  • Buy: Buy

Dextromethorphan hydrobromide monohydrate Chemical Properties,Usage,Production

  • Description Dextromethorphan (DXM) is a dextratrorotatory morphinan with structural similarity to levorphanol, codeine, and morphine. Because of its strong antitussive effects, dextromethorphan is widely used as a cough suppressant. However, it does not provoke opioid activity as is characteristic of several other morphine derivatives. DXM binds to and inhibits NMDA (IC50 = 0.55 μM) and nicotinic receptors (IC50s = 0.7-3.9 μM) and blocks receptor-gated and voltage-gated calcium channels (IC50 = 60 μM) and voltage-gated sodium channels (IC50 = 78 μM). DXM has been used in multimodal analgesic therapies for acute and neuropathic pain.
  • Chemical Properties White Solid
  • Uses An antitussive drug. Orally active synthetic morphine analog. Analgesic (narcotic). Racemethorphan and levomethorpham are controlled substances (opiates).
  • Uses Antitussive;Opioid ligand
  • Definition ChEBI: Dextromethorphan hydrobromide is the hydrobromide and monohydrate of the antitussive drug dextromethorphan. It is a hydrate and a hydrobromide. It contains a dextromethorphan.
  • brand name Benylin DM (Parke-Davis); Dextromethorphan Hydrobromide OROS Tablets (Ciba-Geigy); Drixoral Cough (Schering-Plough HealthCare); PediaCare 1 (McNeil Consumer); Romilar (Hoffmann-LaRoche-International); St. Joseph Cough Syrup (Schering-Plough HealthCare).
  • Biological Activity Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.
  • Toxics Screening Level The Initial Threshold Screening Level (ITSL) is 0.4 μg/m3 annual average.
Dextromethorphan hydrobromide monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Dextromethorphan hydrobromide monohydrate Suppliers
Global(228)Suppliers
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21628
  • Advantage：55
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29858
  • Advantage：58
Dextromethorphan hydrobromide monohydrate Spectrum
6700-34-1, Dextromethorphan hydrobromide monohydrateRelated Search:
  • Other APIs
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Heterocycles
  • Chiral Reagents
  • Aromatics
  • 高端化学
  • 精细化工原料
  • 科研原料
  • 化学试剂
  • 试剂
  • 化工品
  • 原料
  • 医用原料
  • 化工原料
  • 中药对照品
  • 对照品
  • 有机化工
  • 医药原料药
  • 卤代物
  • 盐
  • 医药原料
  • 镇咳药
  • 原料药
  • 呼吸系统用药
  • 小分子抑制剂
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Complex Molecules
  • Allosteric antagonist at NMDA-controlled ion channels; antagonist at voltage-dependent channels
  • C18H30BrNO3
  • 37032
  • C18H25NOHBrH2O
  • C18H28BrNO2
  • 氢溴酸右美沙芬一水合物—仅供出口!
  • 一水合氢溴酸右美沙芬
  • 标准品对照品】DEXTROMETHORPHAN HBR
  • 右美沙芬氢溴酸一水合物
  • 氢溴酸右美沙芬-6700
  • 氢溴酸右美沙芬:HBR:H2O(O-甲基-13C,98%)
  • 氢溴酸右美沙芬DEXTROMETHORPHAN HYDROBROMIDE MONOH
  • 氢溴酸右美沙芬原料药
  • 氢溴酸右美沙芬水合物
  • 氢溴酸右美沙芬一水标准品
  • 右美沙芬溴酸氢
  • 氢溴酸右美沙芬一水合物(CAS号:6700-34-1)
  • 盐酸右美沙芬
  • 氢溴酸右甲吗南杂质
  • 右美沙芬 氢溴酸盐 一水合物
  • 右美沙芬 氢溴酸盐
  • (9S,13S,14S)-3-METHOXY-17-METHYLMORPHINAN 氢溴酸盐
  • 氢溴酸右美沙芬(标准品)
  • 氢溴酸右美沙芬一水
  • 一水氢溴酸右旋美沙芬
  • 氢溴酸右美沙芬一水合物
  • 氢溴酸右旋美沙芬
  • 氢溴酸右美沙芬 ≥99% (TLC)
  • 6700-34-1

Home

My