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8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione

8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Structure
8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
  • CAS No.22316-55-8
  • Chemical Name:8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
  • CBNumber:CB5921872
  • Molecular Formula:C15H11ClN2O2
  • Formula Weight:286.71
  • MOL File:22316-55-8.mol
8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Property
  • Melting point >239°C (dec.)
  • Boiling point 601.8±55.0 °C(Predicted)
  • Density 1.363±0.06 g/cm3(Predicted)
  • Flash point 2℃
  • storage temp. Controlled Substance, -20°C Freezer
  • solubility Acetonitrile (Soluble)
  • pka 7.57±0.20(Predicted)
  • form A neat solid
  • EWG's Food Scores 1
  • FDA UNII MZ4L647O2H
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • Hazard Codes  :F,Xn
  • Risk Statements  :11-20/21/22-36
  • Safety Statements  :16-36/37
  • RIDADR  :UN 1648 3 / PGII
  • WGK Germany  :2
  • Toxicity :mouse,LD50,oral,> 2583mg/kg (2583mg/kg),United States Patent Document. Vol. #3760074,
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H302+H312+H332-H319
  • Precautionary statements P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338
8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: D-049
  • Product name : N-Desmethylclobazam solution
  • Purity: 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging: 1ML
  • Price: ₹19989.9
  • Updated: 2022/06/14
  • Buy: Buy

8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Chemical Properties,Usage,Production

  • Description N-Desmethylclobazam (CRM) (Item No. 18888) is a certified reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam (CRM) positively modulates GABAA receptors (EC50s range from 98 to 151 μM, depending on subunit configuration). This product is intended for research and forensic applications.
  • Description N-Desmethylclobazam (Item No. 18564) is an analytical reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam positively modulates GABAA receptors (EC50s range from 98 to 151 μM, depending on subunit configuration). This product is intended for research and forensic applications.
  • Chemical Properties Off-White Solid
  • Uses The major metabolite of Clobazam Controlled substance (depressant).
  • Definition ChEBI: N-Desmethylclobazam is a benzodiazepine.
  • General Description A Certified Solution Standard for use in LC or GC applications from forensic and forensic toxicology analysis to urine drug testing. N-Desmethylclobazam, found in urine, serum, and plasma, is the pharmacologically active, major metabolite of clobazam.
8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Preparation Products And Raw materials
Raw materials
Preparation Products
8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Suppliers
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8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Spectrum
  • Pharmaceuticals
  • Metabolites & Impurities
  • Intermediates & Fine Chemicals
  • Heterocycles
  • Aromatics
  • 化学试剂
  • 杂质标准品
  • 2316-55-8
  • 氯巴占 EP 杂质 A(N-去甲基氯巴占)
  • 氧异安定杂质1(氧异安定EP杂质A)
  • 8-氯-1-苯基-1H-1,5-苯并二氮杂卓-2,4(3H,5H)-二酮
  • N-去甲基氯巴占
  • 氯巴占杂质 A
  • 氯巴占EP杂质A
  • 22316-55-8
  • 7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione (Norclobazam)
  • N-Desmethylclobazam (nor-Clobazam)
  • Clobazam USP Related Compound A
  • Clobazam Related Compound A
  • Clobazam - Impurity A (Freebase)
  • Clobazam impurity A (Y0000241)
  • N-DesmethylclobazamQ: What is N-Desmethylclobazam Q: What is the CAS Number of N-Desmethylclobazam Q: What is the storage condition of N-Desmethylclobazam Q: What are the applications of N-Desmethylclobazam
  • Clobazam EP Impurity A (N-Desmethylclobazam)
  • N-Desmethyl Clobazam (100 μg/mL in Acetonitrile )
  • Clobazam Impurity 1(Clobazam EP Impurity A)
  • Clobazam EP Impurity A
  • N-Desmethylclobazam (CRM)
  • 7-chloro-5-phenyl-1H-1,5-benzodiazepine-2,4-dione
  • N-Desmethylclobazam solution
  • 8-chloro-1-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione
  • N-Demethylclobazam
  • Einecs 244-909-2
  • Demethylclobazam
  • Clofazin
  • 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 8-chloro-1-phenyl-
  • Norclobazam
  • Desmethylclobazam
  • 7-Chloro-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
  • 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
  • 7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione