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2-Methylpropanedioic acid

2-Methylpropanedioic acid Structure
2-Methylpropanedioic acid
  • CAS No.516-05-2
  • Chemical Name:2-Methylpropanedioic acid
  • CBNumber:CB5713714
  • Molecular Formula:C4H6O4
  • Formula Weight:118.09
  • MOL File:516-05-2.mol
2-Methylpropanedioic acid Property
  • Melting point 128-130 °C (lit.)
  • Boiling point 272.71°C (rough estimate)
  • Density 1.45
  • refractive index 1.4304 (estimate)
  • Flash point 2℃
  • storage temp. Sealed in dry,Room Temperature
  • solubility DMSO (Slightly), Methanol (Slightly)
  • form Crystalline Powder
  • pka 3.07, 5.76(at 25℃)
  • color White
  • Specific Gravity 1.455
  • PH 3.23(1 mM solution);2.6(10 mM solution);2.05(100 mM solution)
  • Water Solubility soluble
  • BRN 1756084
  • CAS DataBase Reference 516-05-2(CAS DataBase Reference)
  • EWG's Food Scores 1
  • FDA UNII 8LL8S712J7
  • NIST Chemistry Reference Methylmalonic acid(516-05-2)
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P302+P352-P305+P351+P338
2-Methylpropanedioic acid Price More Price(5)
  • Brand: Sigma-Aldrich(India)
  • Product number: M54058
  • Product name : Methylmalonic acid
  • Purity: 99%
  • Packaging: 5G
  • Price: ₹6754.8
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: M54058
  • Product name : Methylmalonic acid
  • Purity: 99%
  • Packaging: 25G
  • Price: ₹14678.7
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: M-080
  • Product name : Methylmalonic acid solution
  • Purity: 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging: 1ML
  • Price: ₹10653.3
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: M0568
  • Product name : Methylmalonic Acid
  • Purity: min. 97.0 %
  • Packaging: 25G
  • Price: ₹8600
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: M0568
  • Product name : Methylmalonic Acid
  • Purity: min. 97.0 %
  • Packaging: 100G
  • Price: ₹11900
  • Updated: 2022/05/26
  • Buy: Buy

2-Methylpropanedioic acid Chemical Properties,Usage,Production

  • Chemical Properties white crystalline powder
  • Uses Methylmalonic acid can be used as a substrate in:
    • Esterification reactions by various catalysts.
    • Synthesis of pyrimidinium betaines with formamidine.
    • Synthesis of malonic acid half thioester (MAHT).

  • Uses 2-Methylpropanedioic acid binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
  • Definition ChEBI: Methylmalonic acid is a dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group. It has a role as a human metabolite. It is functionally related to a malonic acid. It is a conjugate acid of a methylmalonate(1-).
  • Biological Functions Methylmalonic acid is capable of diffusing out of cells in which it is being produced, so it may be detected in excess in the blood, CSF, and urine of patients with these various forms of the disease.
  • General Description Methylmalonic acid is an indicator of vitamin B12 deficiency and methylmalonic acidemia. This Certified Spiking Solution? is suitable for use in preparation of calibrators or controls in clinical and diagnostic testing using GC/MS or LC/MS.
  • storage Store at RT
  • Purification Methods The acid crystallises as the hydrate from water. [Beilstein 2 IV 1932.]
2-Methylpropanedioic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methylpropanedioic acid Suppliers
Global(313)Suppliers
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2-Methylpropanedioic acid Spectrum
516-05-2, 2-Methylpropanedioic acidRelated Search:
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  • 甲基丙二酸,10 MM DMSO 溶液
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  • NSC 25201|||MMA|||ISOSUCCINIC ACID|||甲基丙二酸|||METHYLPROPANEDIOIC ACID|||METHYLMALONATE
  • 甲基丙二酸 (13C4, 99%)
  • 甲基缩苹果酸
  • 甲基马来酸/異琥珀酸/2-甲基丙二酸
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  • 異琥珀酸
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  • 516-05-2
  • Methylmalonic acid, 10 mM in DMSO
  • Methyl Malonic Acid / 2-Methylpropanedioc acid
  • Methylmalonic Acid in Acetonitrile
  • Methylmalonic acid in methanol
  • NSC 25201|||MMA|||Isosuccinic acid|||Methylpropanedioic acid|||Methylmalonate
  • 2-Methylmalonic acid
  • METHYLMALONIC ACID
  • AI3-15327
  • AI315327
  • AI3 15327
  • 516-05-2 2-Methylpropanedioic acid C4H6O4
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  • Propanedioic acid, 2-methyl-

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