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Calcium folinatc

Calcium folinatc Structure
Calcium folinatc
  • CAS No.6035-45-6
  • Chemical Name:Calcium folinatc
  • CBNumber:CB5498125
  • Molecular Formula:C20H27CaN7O8
  • Formula Weight:533.56
  • MOL File:6035-45-6.mol
Calcium folinatc Property
  • Melting point 240-250°C
  • alpha D21 +14.9° (c = 1 in water)
  • storage temp. Keep in dark place,Inert atmosphere,2-8°C
  • solubility insoluble in DMSO; insoluble in EtOH; ≥15.04 mg/mL in H2O with gentle warming
  • form powder
  • color Yellow-white to yellow
  • FDA UNII R3W57OBQ5W
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :36/37/38-42/43
  • Safety Statements  :26-36
  • WGK Germany  :3
  • HS Code  :29362900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H335-H317-H319-H334-H315
  • Precautionary statements P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Calcium folinatc Chemical Properties,Usage,Production

  • Chemical Properties yellowish-white to yellow powder
  • Uses Antianemic
  • Uses An intermediate product of the metabolism of Folic Acid. This compound is a mixture of diastereomers.
  • brand name Wellcovorin (GlaxoSmithKline).
  • Biological Activity human lymphoid cell lines were studied for leucovorin requirements to protect from methotrexate (mtx)-induced growth suppression. over a 72h continuous exposure leucovorin provided better protection to the cell lines laz-007 and raji than to the cell line
  • in vivo

    Folinic acid (7.0 mg/kg; intraperitoneal injection; every second day; for 3 weeks; Balb/c young growing male mice) treatment following methotrexate (MTX) administration appears to reverse this growth inhibition (Chronic administration of MTX induces suppression of skeletal growth in mice)[2].

    Animal Model:24 Balb/c young growing male mice aged 3 weeks (11.88 ± 0.25 g)[2]
    Dosage:7.0 mg/kg
    Administration:Intraperitoneal injection; every second day; for 3 weeks
    Result:Following methotrexate (MTX) administration appears to reverse this growth inhibition.
  • IC 50 Human Endogenous Metabolite
Calcium folinatc Preparation Products And Raw materials
Raw materials
Preparation Products
Calcium folinatc Suppliers
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Calcium folinatc Spectrum
6035-45-6, Calcium folinatc Related Search:
  • Miscellaneous Biochemicals
  • Calcium, Calcium Folinatc, Citrovorum Factor
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  • 中间体
  • C20H21CaN7O75H2O
  • C21H25CaN7O75H2O
  • C20H31CaN7O12
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  • 6035-45-6
  • Inhibitor,Folinic acid calcium salt,Folinic Acid Calcium Salt Pentahydrate,Leucovorin calcium salt,inhibit,Antifolate
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  • Leucovorin calcium hydrate
  • Calcium folinatc USP/EP/BP
  • Folinic Acid Calcium Pentahydrate
  • calcium 2-[[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]phenyl]-oxomethyl]amino]pentanedioate pentahydrate
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  • Folidan
  • Foliben
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  • NSC-3590
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  • Calcium folinatc
  • Folinic acid, calcium salt pentahydrate, 95.0-105.0%
  • FOLINIC ACID CALCIUM CELL CULTURE TESTED

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