ChemicalBook > CAS DataBase List > Imperatorin

Imperatorin

Description References

Imperatorin

CAS No.482-44-0
Chemical Name:Imperatorin
CBNumber:CB5355754
Molecular Formula:C16H14O4
Formula Weight:270.28
MOL File:482-44-0.mol

Imperatorin Property

Melting point 98-100°C
Boiling point 333.4°C (rough estimate)
Density 1.1311 (rough estimate)
refractive index 1.4350 (estimate)
storage temp. -20°C
solubility DMSO: ≥5mg/mL
form powder
color off-white to light brown
λmax 301nm(MeOH)(lit.)
Merck 14,4925
InChIKey OLOOJGVNMBJLLR-UHFFFAOYSA-N
LogP 2.983 (est)
CAS DataBase Reference 482-44-0(CAS DataBase Reference)
FDA UNII K713N25C78
NIST Chemistry Reference 7H-furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-(482-44-0)
UNSPSC Code 85151701
NACRES NA.77

Safety

Safety Statements :24/25
WGK Germany :3
RTECS :LV1575000
HS Code :29419090
Hazardous Substances Data :482-44-0(Hazardous Substances Data)

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302
Precautionary statements P264-P270-P301+P312+P330-P501

Imperatorin Price More Price(9)

Brand: Sigma-Aldrich(India)
Product number: I6659
Product name : Imperatorin
Purity: ≥98% (HPLC), powder
Packaging: 5MG
Price: ₹15241.6
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: I6659
Product name : Imperatorin
Purity: ≥98% (HPLC), powder
Packaging: 25MG
Price: ₹51808.45
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: I0904
Product name : Imperatorin
Purity:
Packaging: 25MG
Price: ₹6600
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: I0904
Product name : Imperatorin
Purity:
Packaging: 100MG
Price: ₹14800
Updated: 2022/05/26
Buy: Buy

Brand: ottokemi
Product number: I 5633
Product name : Imperatorin powder, ≥98% (HPLC)
Purity:
Packaging: 25mg
Price: ₹6561
Updated: 2022/05/26
Buy: Buy

Imperatorin Chemical Properties,Usage,Production

Description Imperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.
References https://www.scbt.com/scbt/product/imperatorin-482-44-0
https://pubchem.ncbi.nlm.nih.gov/compound/imperatorin#section=Top
https://en.wikipedia.org/wiki/Imperatorin
Chemical Properties White Solid
Uses Imperatorin (cas# 482-44-0) is a compound useful in organic synthesis.
Definition ChEBI: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.
General Description This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.