Phalloidin-iFluor 405 Conjugate

Description

Phalloidin-iFluor™ 405 Conjugate is a fluorescein-based dye used to label actin filaments (F-actin). Phalloidin binds to F-actin and prevents depolymerization.1 It also inhibits the ATP hydrolysis action of F-actin.2 Phalloidin-iFluor™ 405 can be used to label tissue, cells, and cell-free preparations that have been formaldehyde-fixed and permeabilized. It displays excitation/emission spectra of 400/421 nm, respectively. Phalloidin-iFluor™ 405 can be used at nanomolar concentrations in conjunction with additional dyes for multi-labeling purposes.WARNING This product is not for human or veterinary use.

References

[1] P. DANCKER . Interaction of actin with phalloidin:[J]. Biochimica et Biophysica Acta (BBA) - Protein Structure, 1975, 400 2: Pages 407-414. DOI: 10.1016/0005-2795(75)90196-8
[2] I. LÖW  Th. W  P Dancker. Stabilization of F-actin by phalloidin reversal of the destabilizing effect of cytochalasin B[J]. FEBS Letters, 1975, 54 2: Pages 263-265. DOI: 10.1016/0014-5793(75)80088-3