PD 158780

PD 158780 Structure
PD 158780
  • CAS No.
  • Chemical Name:PD 158780
  • CBNumber:CB5326060
  • Molecular Formula:C14H12BrN5
  • Formula Weight:330.18
  • MOL File:Mol file
PD 158780 Property
  • storage temp. -20°C
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

PD 158780 Chemical Properties,Usage,Production

  • Uses PD 158780 is a potent tyrosine kinase inhibitor of the epidermal growth factor receptor and has been shown to delay substantial growth of tumors in vivo tumor models.
  • Enzyme inhibitor This photosensitive pyridopyrimidine (FW = 330.19 g/mol), known systematically as 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4- d]pyridimine, inhibits EPGFR (epidermal growth factor receptor) proteintyrosine kinase (IC50 = 8 pM). In addition, PD 158780 inhibits heregulinstimulated autophosphorylation in SK-BR-3 (IC50 = 49 nM) and MDA-MB- 453 (IC50 = 52 nM) breast carcinomas.
PD 158780 Preparation Products And Raw materials
Raw materials
Preparation Products
PD 158780 Suppliers
Global(40)Suppliers
  • Supplier： Cayman Chemical Company
  • Tel：800-364-9897
  • Email：sales@caymanchem.com
  • Country：China
  • ProdList：27736
  • Advantage：58
PD 158780 Spectrum
PD 158780Related Search:
  • 细胞生物学试剂
  • EGFR家族抑制剂(PD158780)
  • PD 158780
  • 4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE

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